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Smad3 Protein

Known as: Madh3 Protein, Smad3 Protein [Chemical/Ingredient] 
A receptor-regulated smad protein that undergoes PHOSPHORYLATION by ACTIVIN RECEPTORS, TYPE I. Activated Smad3 can bind directly to DNA, and it… 
National Institutes of Health

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SMAD3 protein, human

Papers overview

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2020
2020
Smad3 gene C‐terminal phosphorylation site mutation aggravates CCl4‐induced inflammation in mice
The expression of C‐terminal phosphorylated Smad3 (pSmad3C) is down‐regulated with the progression of liver disease. Thus, we… 
2016
2016
MicroRNA-23a regulates epithelial-to-mesenchymal transition in endometrial endometrioid adenocarcinoma by targeting SMAD3
To investigate the role of total cellular microRNA (miRNA) in regulating epithelial-to-mesenchymal transition (EMT) during human… 
2015
2015
hCLP46 increases Smad3 protein stability via inhibiting its ubiquitin-proteasomal degradation
Dear Editor, hCLP46 (human CAP10-like protein 46 kDa) was initially isolated and identified from human acute myeloid leukemia… 
2013
2013
Endothelial Dysfunction Exacerbates Renal Interstitial Fibrosis through Enhancing Fibroblast Smad3 Linker Phosphorylation in the Mouse Obstructed Kidney
Endothelial dysfunction and enhanced transforming growth factor-β (TGF-β)/Smad3 signalling are common features of progressive… 
2012
2012
Long-term stable cationic solid lipid nanoparticles for the enhanced intracellular delivery of SMAD3 antisense oligonucleotides in activated murine macrophages.
PURPOSE Long-term stable cationic solid lipid nanoparticles (cSLNs) were formulated to transfer SMAD3 antisense oligonucleotides… 
2012
2012
Smad3 shRNA抑制TGFβ1对HSC-T6细胞活化的抗肝纤维化作用
目的观察Smad3 shRNA对TGFβ1作用于大鼠HSC-T6细胞增殖、细胞周期以及分泌肝纤维化胶原的影响。方法Smad3 shRNA慢病毒感染HSC-T6,应用流式细胞仪检测其感染率,Real-time PCR检测对Smad3 mRNA… 
2009
2009
Novel regulation of Smad3 oligomerization and DNA binding by its linker domain.
Smad proteins are key effectors of the transforming growth factor beta (TGFbeta) signaling pathway in mammalian cells. Smads are… 
2002
2002
Involvement of Smad proteins in TGF-beta and activin A-induced apoptosis and growth inhibition of liver cells.
1998
1998
239 ヒト大腸癌組織における Smad3 遺伝子異常の検索
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