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Sisomicin

Known as: Sisomicin [Chemical/Ingredient], (2R,3R,4R,5R)-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol, Sisomycin 
A broad-spectrum aminoglycoside antibiotic isolated from Micromonospora inyoensis. Sisomicin is strucurally similar to gentamicin but has a unique… 
National Institutes of Health

Related topics

Related topics

18 relations

Broader (2)

Anti-Bacterial AgentsProtein Synthesis Inhibitors

Narrower (4)

ExtramycinSipralinatSiseptinpentisomicin
In BloodSisomicin SulfateSisomicin:Susc:Pt:Isolate:OrdQn:Gradient stripSisomicin:Susc:Pt:Isolate:OrdQn:MIC

Papers overview

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1985
1985
The comparative activity of eleven aminocyclitol antibiotics against 773 aerobic gram-negative rods and staphylococci isolated from infected hospitalized patients.
The minimum inhibitory concentrations (MICs) of 11 aminocyclitol antibiotics were determined for 773 recent clinical isolates… 
Review
1984
Review
1984
The key role of aminoglycosides in antibacterial therapy and prophylaxis.
The discovery that aminosugars found in nature kill common bacteria initiated use of a new class of antibiotics that have played… 
1981
1981
An R plasmid of broad host-range, coding for resistance to nine antimicrobial agents endemic in Gram-negative nosocomial isolates.
Of 3952 clinical isolates of Enterobacteriaceae, 246 exhibited resistance to at least carbenicillin, gentamicin and tobramycin… 
1980
1980
Antimicrobial activity of netilmicin in comparison with gentamicin, sisomicin, tobramycin, and amikacin and their resistance patterns.
The antimicrobial activity of netilmicin, gentamicin, sisomicin, tobramycin and amikacin was determined by means of the… 
1978
1978
Chemical modification of some gentamicins and sisomicin at the 3''-position.
Chemical and photochemical oxidative methods of de-N-methylation of some gentamicins and sisomicins at the 3''-position are… 
1978
1978
Semisynthetic aminoglycoside antibacterials. 6. Synthesis of sisomicin, Antibiotic G-52, and novel 6'-substituted analogues of sisomicin from aminoglycoside 66-40C.
The discovery of aminoglycoside 66-40C, a novel dimeric, unsaturated imine produced by Micromonospora inyoensis, afforded a… 
1978
1978
Synergism of penicillin or ampicillin combined with sissomicin or netilmicin against enterococci.
Highly Cited
1976
Highly Cited
1976
Antibiotic synergism in enterococcal endocarditis.
The recognition of enterococci highly resistant to streptomycin (S) raises questions concerning the choice of aminoglycoside in… 
1976
1976
Die antimikrobielle Wirksamkeit von Sisomicin
ZusammenfassungDas Prinzip einer sinnvollen Antibiotika-Kombination besteht in der simultanen Gabe von Antibiotika mit… 
1976
1976
Sisomicin versus Gentamicin
: In a comparison of the antibacterial in-vitro activity of sisomicin, gentamicin, and tobramycine, sisomicin showed a higher…