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Sisomicin

Known as: Sisomicin [Chemical/Ingredient], (2R,3R,4R,5R)-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol, Sisomycin 
A broad-spectrum aminoglycoside antibiotic isolated from Micromonospora inyoensis. Sisomicin is strucurally similar to gentamicin but has a unique… 
National Institutes of Health

Related topics

Related topics

18 relations

Broader (2)

Anti-Bacterial AgentsProtein Synthesis Inhibitors

Narrower (4)

ExtramycinSipralinatSiseptinpentisomicin
In BloodSisomicin SulfateSisomicin:Susc:Pt:Isolate:OrdQn:Gradient stripSisomicin:Susc:Pt:Isolate:OrdQn:MIC

Papers overview

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Highly Cited
2003
Highly Cited
2003
Determination of tobramycin in serum using liquid chromatography-tandem mass spectrometry and comparison with a fluorescence polarisation assay.
Review
1998
Review
1998
High-performance liquid chromatographic analysis of aminoglycoside antibiotics.
1989
1989
Determination of aminoglycosides in pharmaceutical formulations--II. High-performance liquid chromatography.
1984
1984
An automated high-performance liquid chromatographic method for the determination of aminoglycosides in serum using pre-column sample clean-up and derivatization.
Highly Cited
1982
Highly Cited
1982
An interaction of aminoglycoside antibiotics with Ca binding to lipid monolayers and to biomembranes.
1980
1980
Outbreak of amikacin-resistant Enterobacteriaceae in an intensive care nursery.
An outbreak of amikacin-resistant Enterobacteriaceae (KES) occurred in the Intensive Care Nursery (ICN) of the Louisville General… 
Highly Cited
1979
Highly Cited
1979
A Randomized Comparative Trial of Three Aminoglycosides—Comparison of Continuous Infusions of Gentamicin, Aaikacin and Sisomicin Combined with Carbenicillin in the Treatment of Infections in…
Continuous infusions of gentamicin, amikacin or sisomicin combined with carbenicillin were compared in a randomized study in the… 
Highly Cited
1977
Highly Cited
1977
A comparative trial of sisomicin therapy by intermittent versus continuous infusion
AbstractOne hundred and thirty-nine febrile episodes in 120 patients were treated with sisomicin after a combination of… 
Review
1975
Review
1975
A gentamycin resistance plasmid in Staphylococcus aureus.
Drug resistance in Staphylococcus aureus is frequently mediated by non-chromosomal DNA molecules referred to as R plasmids. So… 
Highly Cited
1973
Highly Cited
1973
Sisomicin: Evaluation In Vitro and Comparison with Gentamicin and Tobramycin
Sisomicin is a new antibiotic produced by Micromonospora inyoensis. The in vitro activities of sisomicin, gentamicin, and… 
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