Sisomicin

Known as: Sisomicin [Chemical/Ingredient], (2R,3R,4R,5R)-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol, Sisomycin 
A broad-spectrum aminoglycoside antibiotic isolated from Micromonospora inyoensis. Sisomicin is strucurally similar to gentamicin but has a unique… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1972-2018
020406019722018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1976
1976
An antibody induced in rabbits against a gentamicin-bovine serum albumin conjugate cross-reacted with the chemically related… (More)
Is this relevant?
1976
1976
A sisomicin fermentation carried out in the presence of (methyl-14C)-L-methionine resulted in a crude mixture, composed of methyl… (More)
Is this relevant?
1975
1975
Studies were conducted in 30 patients with neoplastic diseases. Twelve patients received sisomicin intramuscularly at doses of 20… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
Is this relevant?
1975
1975
Using a randomized crossover design involving 12 normal subjects, we studied comparatively the pharmacokinetics and tolerance of… (More)
Is this relevant?
1975
1975
A preliminary study was conducted with sisomicin, a new aminoglycoside antibiotic. The drug was administered to 40 patients in… (More)
Is this relevant?
1975
1975
Levels of rifampin, gentamicin, sisomicin, and cephalothin in normal and osteomyelitic rabbit bones were measured, and the… (More)
Is this relevant?
1975
1975
Utilizing a mutant of Micromonospora inyoensis which requires the addition of 2-deoxystreptamine for sisomicin production, the… (More)
Is this relevant?
1974
1974
The activity of sisomicin, gentamicin, and tobramycin against 273 clinical bacterial isolates was about equal (except for greater… (More)
Is this relevant?
1973
1973
Sisomicin is a new antibiotic produced by Micromonospora inyoensis. The in vitro activities of sisomicin, gentamicin, and… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
1972
1972
Gentamicin, sisomicin, tobramycin, and kanamycin were compared in parallel tests in vitro and in vivo against a variety of… (More)
  • table 1
  • table 2
  • table 3
  • table 4
  • table 5
Is this relevant?