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Sisomicin

Known as: Sisomicin [Chemical/Ingredient], (2R,3R,4R,5R)-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol, Sisomycin 
A broad-spectrum aminoglycoside antibiotic isolated from Micromonospora inyoensis. Sisomicin is strucurally similar to gentamicin but has a unique… Expand
National Institutes of Health

Papers overview

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Review
2012
Review
2012
Plazomicin (formerly ACHN-490) is a next-generation aminoglycoside that was synthetically derived from sisomicin by appending a… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND the emergence of carbapenemases in Enterobacteriaceae is driving a search for therapeutic alternatives. We tested ACHN… Expand
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2010
2010
A simple method for the simultaneous determination of dihydrostreptomycin, spectinomycin, spiramycin, streptomycin, tilmicosin… Expand
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Highly Cited
2010
Highly Cited
2010
ABSTRACT ACHN-490 is a neoglycoside, or “next-generation” aminoglycoside (AG), that has been identified as a potentially useful… Expand
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2003
2003
We have developed a tandem mass spectrometry (LC-MS-MS) method for measuring tobramycin concentrations in serum samples and have… Expand
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Highly Cited
2001
Highly Cited
2001
ABSTRACT Two clonally unrelated Pseudomonas aeruginosa clinical strains, RON-1 and RON-2, were isolated in 1997 and 1998 from… Expand
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Review
1995
Review
1995
Resistance of Neisseria gonorrhoeae to antimicrobial agents continues to spread and intensify. Choosing an antimicrobial regimen… Expand
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1975
1975
Using a randomized crossover design involving 12 normal subjects, we studied comparatively the pharmacokinetics and tolerance of… Expand
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1973
1973
Sisomicin is a new antibiotic produced by Micromonospora inyoensis. The in vitro activities of sisomicin, gentamicin, and… Expand
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1972
1972
Gentamicin, sisomicin, tobramycin, and kanamycin were compared in parallel tests in vitro and in vivo against a variety of… Expand
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