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Sirtuin 3

Known as: Silent Mating Type Information Regulation 2 Homolog 3, Sirtuin 3 [Chemical/Ingredient] 
A sirtuin family member found primarily in MITOCHONDRIA. It is a multifunctional enzyme that contains a NAD-dependent deacetylase activity that is… 
National Institutes of Health

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In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects

Broader (1)

SIRT3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Sirtuin 3 attenuates amyloid-β induced neuronal hypometabolism
Alzheimer’s disease (AD) is manifested by regional cerebral hypometabolism. Sirtuin 3 (Sirt3) is localized in mitochondria and… 
2018
2018
SIRT 3 restricts HBV transcription and replication via epigenetic regulation of cccDNA involving SUV 39 H 1 and SETD 1 A histone methyltransferases
Hepatitis B virus (HBV) infection remains a major health problem worldwide. Maintenance of the covalently closed circular DNA… 
2018
2018
Sirtuin 3 silencing improves oxaliplatin efficacy through acetylation of MnSOD in colon cancer
Sirtuin 3 (SIRT3) is the major mitochondria deacetylase and regulates ROS levels by targeting several key proteins, such as those… 
2018
2018
A6555 Sirtuin 3-induced macrophage autophagy in regulating NLRP3 inflammasome activation
Objectives: Defective autophagy of monocytes or macrophages might result in NLRP3 inflammasome activation and cause vascular… 
2017
2017
Sirt3 Deficiency Increased the Vulnerability of Pancreatic Beta Cells to Oxidative Stress-Induced Dysfunction
Abstract Aims: Hyperlipidemia-induced oxidative stress is considered to be one of the main pathogenic factors that contribute to… 
2017
2017
Sirt3 Deficiency Increased the Vulnerability of Pancreatic Beta Cells to Oxidative Stress-Induced Dysfunction.
AIMS Hyperlipidemia-induced oxidative stress is considered to be one of the main pathogenic factors that contribute to pancreatic… 
2016
2016
ID: 117: SIRT3, THE MAJOR ANTI-AGING MITOCHONDRIAL DEACETYLASE, IS IMPORTANT FOR PREVENTING PULMONARY FIBROSIS
Objectives Alveolar epithelial cell (AEC) injury from ‘exaggerated’ lung aging and mitochondrial dysfunction play vital roles in… 
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