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Sirtuin 3

Known as: Silent Mating Type Information Regulation 2 Homolog 3, Sirtuin 3 [Chemical/Ingredient] 
A sirtuin family member found primarily in MITOCHONDRIA. It is a multifunctional enzyme that contains a NAD-dependent deacetylase activity that is… 
National Institutes of Health

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In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects
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Broader (1)

SIRT3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
SIRTUIN 3, ENDOTHELIAL METABOLIC REPROGRAMMING AND HEART FAILURE WITH PRESERVED EJECTION FRACTION.
The incidences of heart failure with preserved ejection fraction (HFpEF) are increased in the aged populations as well as… 
Review
2018
Review
2018
Reactive Oxygen and Nitrogen Species Regulate Key Metabolic, Anabolic, and Catabolic Pathways in Skeletal Muscle
Reactive oxygen and nitrogen species (RONS) are important cellular regulators of key physiological processes in skeletal muscle… 
2018
2018
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3‐TGF‐&bgr;‐Smad signaling pathway
2018
2018
SIRT3 prevents angiotensin II-induced renal tubular epithelial-mesenchymal transition by ameliorating oxidative stress and mitochondrial dysfunction
2018
2018
Sirtuin 3 attenuates amyloid-β induced neuronal hypometabolism
Alzheimer’s disease (AD) is manifested by regional cerebral hypometabolism. Sirtuin 3 (Sirt3) is localized in mitochondria and… 
2018
2018
SIRT3 restricts hepatitis B virus transcription and replication through epigenetic regulation of covalently closed circular DNA involving suppressor of variegation 3‐9 homolog 1 and SET domain…
Hepatitis B virus (HBV) infection remains a major health problem worldwide. Maintenance of the covalently closed circular DNA… 
2017
2017
Sirtuin 3 is required for osteogenic differentiation through maintenance of PGC-1ɑ-SOD2-mediated regulation of mitochondrial function
Osteogenic differentiation is crucial for the maintenance of bone homeostasis. Sirtuin 3 (SIRT3), a member of sirtuins family… 
Highly Cited
2017
Highly Cited
2017
SOD2 and Sirt3 Control Osteoclastogenesis by Regulating Mitochondrial ROS
Reactive oxygen species (ROS) are an indispensable element of cellular signal transduction in various cell types, including bone… 
2017
2017
Sirtuin 3 rescues neurons through the stabilisation of mitochondrial biogenetics in the virally-expressing mutant α-synuclein rat model of parkinsonism
Highly Cited
2009
Highly Cited
2009
Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice.
Sirtuin 3 (SIRT3) is a member of the sirtuin family of proteins that promote longevity in many organisms. Increased expression of… 
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