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Silencer Elements, Transcriptional

Known as: Element, Silencer, Transcriptional Silencer Elements, Element, Transcriptional Silencer 
Nucleic acid sequences that are involved in the negative regulation of GENETIC TRANSCRIPTION by chromatin silencing.
National Institutes of Health

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aspects of radiation effectsphysiological aspects

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proU silencer

Papers overview

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Highly Cited
2004
Highly Cited
2004
MAZ Elements Alter Transcription Elongation and Silencing of the Fibroblast Growth Factor Receptor 2 Exon IIIb*
The fibroblast growth factor receptor 2 (FGFR2) gene exons IIIb and IIIc are alternatively spliced in a mutually exclusive and… 
Highly Cited
2003
Highly Cited
2003
Morpholino Antisense Oligonucleotide-Mediated Gene Knockdown During Thymocyte Development Reveals Role for Runx3 Transcription Factor in CD4 Silencing During Development of CD4−/CD8+ Thymocytes 1
During thymic T cell development, immature CD4+/CD8+ thymocytes develop into either CD4+/CD8− helper or CD4−/CD8+ CTLs. The… 
Review
1999
Review
1999
Breast tumor aromatase: functional role and transcriptional regulation.
Aromatase has been shown to be expressed at a higher level in human breast cancer tissue than in normal breast tissue, by means… 
Highly Cited
1999
Highly Cited
1999
4.5 kb of the rat tyrosine hydroxylase 5' flanking sequence directs tissue specific expression during development and contains consensus sites for multiple transcription factors.
Highly Cited
1998
Highly Cited
1998
An Sp1-binding Silencer Element Is a Critical Negative Regulator of the Megakaryocyte-specific αIIb Gene*
The Sp1 family of transcription factors are often involved in the regulated expression of TATA-less genes, frequently enhancing… 
Highly Cited
1998
Highly Cited
1998
Gene organization and promoter function for CC chemokine receptor 5 (CCR5).
CC chemokine receptor 5 (CCR5) functions physiologically as a receptor for the leukocyte chemoattractants macrophage inflammatory… 
Highly Cited
1996
Highly Cited
1996
Promoter Region of the Rat m4 Muscarinic Acetylcholine Receptor Gene Contains a Cell Type-specific Silencer Element (*)
We describe here the characterization of the rat m4 muscarinic acetylcholine receptor gene and the identification of its… 
Highly Cited
1995
Highly Cited
1995
Silencer Elements Modulate the Expression of the Gene for the Neuron-Glia Cell Adhesion Molecule, Ng-CAM (*)
The combined factors that regulate the expression of cell adhesion molecules (CAMs) during development of the nervous system are… 
Highly Cited
1989
Highly Cited
1989
Identification of a transcriptional silencer in the 5'-flanking region of the human epsilon-globin gene.
We have studied the 5'-flanking sequences required for the transcriptional regulation of human epsilon-globin gene expression. A… 
Highly Cited
1989
Highly Cited
1989
Blockage of αβ T-cell development by TCR γδ transgenes
T LYMPHOCYTES recognize antigens by means of T-cell receptors (TCR) composed of αβ (refs 1–3) or γδ heterodimers4–6. The… 
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