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Signaling Lymphocytic Activation Molecule, human

Known as: CD150 antigen, human, SLAMF1 protein, human, signaling lymphocytic activation molecule family member 1, human 
Signaling lymphocytic activation molecule (335 aa, ~37 kDa) is encoded by the human SLAMF1 gene. This protein is involved in immune cell regulation… 
National Institutes of Health

Related topics

Related topics

5 relations
SLAMF1 geneSignal TransductionSignaling Pathway Gene

Broader (2)

Signaling Lymphocytic Activation Molecule FamilySignaling Lymphocytic Activation Molecule Family Member 1

Papers overview

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Highly Cited
2010
Highly Cited
2010
Germinal Center T Follicular Helper Cell IL-4 Production Is Dependent on Signaling Lymphocytic Activation Molecule Receptor (CD150)
CD4 T cell help is critical for the generation and maintenance of germinal centers (GCs), and T follicular helper (TFH) cells are… 
Highly Cited
2005
Highly Cited
2005
Signaling lymphocytic activation molecule-associated protein controls NKT cell functions.
X-linked lymphoproliferative disease (XLP) is a fatal immunological disorder that typically manifests following EBV infection… 
Highly Cited
2005
Highly Cited
2005
SAP controls the cytolytic activity of CD8+ T cells against EBV-infected cells.
The adaptor protein SAP regulates signaling through signaling lymphocytic activation molecule (SLAM)-family receptors expressed… 
Highly Cited
2003
Highly Cited
2003
Wild-type measles virus induces large syncytium formation in primary human small airway epithelial cells by a SLAM(CD150)-independent mechanism.
Highly Cited
2001
Highly Cited
2001
Measles Viruses on Throat Swabs from Measles Patients Use Signaling Lymphocytic Activation Molecule (CDw150) but Not CD46 as a Cellular Receptor
ABSTRACT Both CD46 and signaling lymphocytic activation molecule (SLAM) have been shown to act as cellular receptors for measles… 
Highly Cited
2001
Highly Cited
2001
CD150 Association with Either the SH2-Containing Inositol Phosphatase or the SH2-Containing Protein Tyrosine Phosphatase Is Regulated by the Adaptor Protein SH2D1A1
CD150 (SLAM/IPO-3) is a cell surface receptor that, like the B cell receptor, CD40, and CD95, can transmit positive or negative… 
Highly Cited
1999
Highly Cited
1999
Molecular and functional characterization of mouse signaling lymphocytic activation molecule (SLAM): differential expression and responsiveness in Th1 and Th2 cells.
Optimal T cell activation and expansion require engagement of the TCR plus costimulatory signals delivered through accessory… 
Highly Cited
1997
Highly Cited
1997
Soluble and Membrane-bound Forms of Signaling Lymphocytic Activation Molecule (SLAM) Induce Proliferation and Ig Synthesis by Activated Human B Lymphocytes
In this study it is shown that both membrane-bound and soluble forms of signaling lymphocytic activation molecule (SLAM) induce… 
Highly Cited
1997
Highly Cited
1997
Reversal of human allergic T helper 2 responses by engagement of signaling lymphocytic activation molecule.
Allergen-specific Th2 cells accumulate at high frequencies in the skin of patients with atopic dermatitis (AD), where they… 
Highly Cited
1997
Highly Cited
1997
Engagement of the signaling lymphocytic activation molecule (SLAM) on activated T cells results in IL-2-independent, cyclosporin A-sensitive T cell proliferation and IFN-gamma production.
The expression and function of the novel signaling lymphocytic activation molecule (SLAM) are described. SLAM is present on… 
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