Signal Recognition Particle

Known as: signal recognition particle (SRP), SRP, Particle, Signal Recognition 
A cytosolic ribonucleoprotein complex that acts to induce elongation arrest of nascent presecretory and membrane proteins until the ribosome becomes… (More)
National Institutes of Health

Related topics

Related topics

19 relations

Narrower (4)

7SL RNAFFC protein, ArabidopsisFfh protein, E coliSRP19 protein, human
In BloodProcess of secretionProtein Sorting SignalsSignal Peptides
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Broader (1)

Ribonucleoproteins

Papers overview

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Review
2017
Review
2017
A Comprehensive Overview on Myositis-Specific Antibodies: New and Old Biomarkers in Idiopathic Inflammatory Myopathy.
Autoantibodies specific for idiopathic inflammatory myopathy (myositis-specific autoantibodies (MSAs)) are clinically useful… (More)
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Review
2009
Review
2009
Protein targeting by the signal recognition particle.
Protein targeting by the signal recognition particle (SRP) is universally conserved and starts with the recognition of a signal… (More)
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Highly Cited
2006
Highly Cited
2006
Anti-signal recognition particle autoantibodies: marker of a necrotising myopathy.
OBJECTIVE To elucidate the clinical importance of the anti-signal recognition particle (SRP) autoantibody in patients with… (More)
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Review
2005
Review
2005
Targeting proteins to membranes: structure of the signal recognition particle.
In all three kingdoms of life, co-translational targeting of secretory and membrane proteins to the prokaryotic plasma membrane… (More)
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Highly Cited
2004
Highly Cited
2004
Substrate twinning activates the signal recognition particle and its receptor
Signal sequences target proteins for secretion from cells or for integration into cell membranes. As nascent proteins emerge from… (More)
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Highly Cited
2004
Highly Cited
2004
Structure of the signal recognition particle interacting with the elongation-arrested ribosome
Cotranslational translocation of proteins across or into membranes is a vital process in all kingdoms of life. It requires that… (More)
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Highly Cited
2002
Highly Cited
2002
Myopathy with antibodies to the signal recognition particle: clinical and pathological features.
OBJECTIVES To study myopathies with serum antibodies to the signal recognition particle (SRP), an unusual, myositis specific… (More)
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Review
2001
Review
2001
The signal recognition particle.
The signal recognition particle (SRP) and its membrane-associated receptor (SR) catalyze targeting of nascent secretory and… (More)
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Highly Cited
2000
Highly Cited
2000
Crystal structure of the ribonucleoprotein core of the signal recognition particle.
The signal recognition particle (SRP), a protein-RNA complex conserved in all three kingdoms of life, recognizes and transports… (More)
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Highly Cited
1990
Highly Cited
1990
Antibody to signal recognition particle in polymyositis.
Using immunoprecipitation, we identified 13 patients with antibodies to the signal recognition particle (SRP) from a collection… (More)
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