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Signal Recognition Particle

Known as: signal recognition particle (SRP), SRP, Particle, Signal Recognition 
A cytosolic ribonucleoprotein complex that acts to induce elongation arrest of nascent presecretory and membrane proteins until the ribosome becomes… 
National Institutes of Health

Related topics

Related topics

19 relations

Narrower (4)

7SL RNAFFC protein, ArabidopsisFfh protein, E coliSRP19 protein, human
In BloodProcess of secretionProtein Sorting SignalsSignal Peptides

Broader (1)

Ribonucleoproteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
The Trypanosomatid Signal Recognition Particle Consists of Two RNA Molecules, a 7SL RNA Homologue and a Novel tRNA-like Molecule*
Trypanosomatids are ancient eukaryotic parasites affecting humans and livestock. Here we report that the trypanosomatid signal… 
2002
2002
Conformational change of the N-domain on formation of the complex between the GTPase domains of Thermus aquaticus Ffh and FtsY.
Highly Cited
1999
Highly Cited
1999
SecA Is Required for the Insertion of Inner Membrane Proteins Targeted by the Escherichia coli Signal Recognition Particle*
Recent work has demonstrated that the signal recognition particle (SRP) is required for the efficient insertion of many proteins… 
Highly Cited
1997
Highly Cited
1997
The N-domain of the signal recognition particle 54-kDa subunit promotes efficient signal sequence binding.
The signal recognition particle 54-kDa subunit (SRP54) binds to the signal sequences of nascent presecretory and transmembrane… 
Highly Cited
1989
Highly Cited
1989
SecB functions as a cytosolic signal recognition factor for protein export in E. coli
1988
1988
Yeast gene SRP1 (serine-rich protein). Intragenic repeat structure and identification of a family of SRP1-related DNA sequences.
Highly Cited
1985
Highly Cited
1985
A structural and functional analysis of the docking protein. Characterization of active domains by proteolysis and specific antibodies.
Highly Cited
1984
Highly Cited
1984
Signal recognition particle is required for co-translational insertion of cytochrome P-450 into microsomal membranes.
Insertion of newly synthesized P-450(1), the major phenobarbital-inducible form of rabbit liver microsomal cytochrome P-450, into… 
1984
1984
Role of signal recognition particle in the membrane assembly of Sindbis viral glycoproteins.
We have investigated the role of signal recognition particle (SRP) in the biosynthesis of Sindbis glycoproteins by translating… 
1976
1976
Catalytic activity of cytochromes c and c1 in mitochondria and submitochondrial particles.
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