Serotonin 5-HT4 Receptor Antagonists

Known as: 5-HT4 Antagonist, Serotonin 5 HT4 Receptor Antagonists, Antagonists, 5-HT4 
Drugs that bind to but do not activate SEROTONIN 5-HT4 RECEPTORS, thereby blocking the actions of SEROTONIN or SEROTONIN RECEPTOR AGONISTS.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2016
02419922016

Papers overview

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2015
2015
KEY POINTS Luminal lipid in the duodenum modulates gastroduodenal functions via the release of gut hormones and mediators such as… (More)
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2007
2007
Serotonin receptors are potential targets for treating functional bowel disorders. This study investigated the functional roles… (More)
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2007
2007
Serotonin [5-hydroxytryptamine (5-HT)] acts as a modulator of colonic motility and secretion. We characterized the action of the… (More)
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2004
2004
1. 5-Hydroxytryptamine (5-HT) modulates the motility and secretion of the gastrointestinal tract. To examine the direct effect of… (More)
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2002
2002
We investigated, using single-unit recordings in chloral hydrate-anaesthetized rats, the role of serotonin 4 (5-HT4) receptors in… (More)
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2002
2002
In the present study, the ability of 5-hydroxytryptamine-4 (5-HT4) receptors in the hippocampus to enhance locomotor activity in… (More)
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1999
1999
Inhaled 5-hydroxytryptamine (5-HT) causes bronchoconstriction in asthmatics, and 5-HT plasma levels are elevated in asthma… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND & AIMS The role of 5-hydroxytryptamine (5-HT) in regulating the peristaltic reflex in humans is unknown. The neural… (More)
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1996
1996
In the rat distal colon, 5-hydroxytryptamine (5-HT)-induced Cl- secretion is seen as a rise in short circuit current (Isc). We… (More)
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Highly Cited
1993
Highly Cited
1993
The receptor specificity of serotonin (5-HT) agonist-induced facilitation of dopamine (DA) release was assessed by using in vivo… (More)
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