Serine Protease Hepsin

Known as: EC 3.4.21.106 
Serine protease hepsin (417 aa, ~45 kDa) is encoded by the human HPN gene. This protein is involved in proteolysis.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2015
0119972015

Papers overview

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2015
2015
Uromodulin is the most abundant protein in the urine. It is exclusively produced by renal epithelial cells and it plays key roles… (More)
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2012
2012
The serine protease hepsin is highly upregulated in prostate cancer and is implicated in tumor progression. Therefore, specific… (More)
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2011
2011
The matrix metalloproteinase (MMP) family is believed to play a role in the ovulatory process because MMP inhibitors block oocyte… (More)
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2009
2009
The transmembrane serine protease hepsin is one of the most highly upregulated genes in prostate cancer. Here, we investigated… (More)
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2008
2008
BACKGROUND Hepsin is a type II transmembrane serine protease originally identified in the human liver as a cDNA clone. Hepsin was… (More)
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Highly Cited
1997
Highly Cited
1997
Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth, allow… (More)
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