Serine-Arginine Splicing Factors

Estrogen is a steroid hormone that has critical roles in reproductive development, bone homeostasis, cardiovascular remodeling… Expand

Alternative splicing (AS) is a key process underlying the expansion of proteomic diversity and the regulation of gene expression… Expand

Resisting Repeats A set of diseases, including myotonic dystrophy, are caused by the expansion of a simple repeat in genomic DNA… Expand

Formation of synapses requires specific cellular interactions that organize pre- and postsynaptic compartments. The neuroligin… Expand

In violation of the 'one gene, one polypeptide' rule, alternative splicing allows individual genes to produce multiple protein… Expand

Alternative splicing is one of the most important mechanisms to generate a large number of mRNA and protein isoforms from the… Expand

Calcium pumps of the plasma membrane (also known as plasma membrane Ca(2+)-ATPases or PMCAs) are responsible for the expulsion of… Expand

P-type and Q-type calcium channels mediate neurotransmitter release at many synapses in the mammalian nervous system. The α1A… Expand

Alternative splicing of pre-mRNAs is a powerful and versatile regulatory mechanism that can effect quantitative control of gene… Expand

The inclusion of the 270-nucleotide human fibronectin ED1 exon in HeLa cells requires the presence of a centrally located 81… Expand