Serine-Arginine Splicing Factors

Known as: Splicing Factors, Serine-Arginine, SR-Rich Splicing Proteins, Splicing Proteins, Serine-Arginine-Rich 
A family of regulatory factors essential for constitutive and alternative splicing in RNA metabolism.
National Institutes of Health

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In BloodProcess of secretionagonistsantagonists & inhibitors
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Papers overview

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Highly Cited
2012
Highly Cited
2012
Psip1/Ledgf p52 Binds Methylated Histone H3K36 and Splicing Factors and Contributes to the Regulation of Alternative Splicing
Increasing evidence suggests that chromatin modifications have important roles in modulating constitutive or alternative splicing… (More)
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2006
2006
Molecular Evolution of Serine/Arginine Splicing Factors Family (SR) by Positive Selection
The serine-rich (SR) protein family is involved in the pre-mRNA splicing process and the DNA sequences of the corresponding genes… (More)
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Review
2005
Review
2005
Function of alternative splicing.
Alternative splicing is one of the most important mechanisms to generate a large number of mRNA and protein isoforms from the… (More)
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Highly Cited
2005
Highly Cited
2005
ASF/SF2-Regulated CaMKIIδ Alternative Splicing Temporally Reprograms Excitation-Contraction Coupling in Cardiac Muscle
The transition from juvenile to adult life is accompanied by programmed remodeling in many tissues and organs, which is key for… (More)
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Highly Cited
2005
Highly Cited
2005
Alternative Splicing Events Identified in Human Embryonic Stem Cells and Neural Progenitors
Human embryonic stem cells (hESCs) and neural progenitor (NP) cells are excellent models for recapitulating early neuronal… (More)
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Highly Cited
2005
Highly Cited
2005
Depletion of TDP 43 overrides the need for exonic and intronic splicing enhancers in the human apoA-II gene
Exon 3 of the human apolipoprotein A-II (apoA-II) gene is efficiently included in the mRNA although its acceptor site is… (More)
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Highly Cited
2002
Highly Cited
2002
De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1.
Previous studies have demonstrated that several splice variants are derived from both the caspase 9 and Bcl-x genes in which the… (More)
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Review
2001
Review
2001
Role of alternative splicing in generating isoform diversity among plasma membrane calcium pumps.
Calcium pumps of the plasma membrane (also known as plasma membrane Ca(2+)-ATPases or PMCAs) are responsible for the expulsion of… (More)
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Review
1998
Review
1998
Alternative splicing of pre-mRNA: developmental consequences and mechanisms of regulation.
Alternative splicing of pre-mRNAs is a powerful and versatile regulatory mechanism that can effect quantitative control of gene… (More)
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Highly Cited
1993
Highly Cited
1993
A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding.
The inclusion of the 270-nucleotide human fibronectin ED1 exon in HeLa cells requires the presence of a centrally located 81… (More)
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