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Semisynthetic Vaccines

Known as: Vaccines, Semisynthetic 
National Institutes of Health

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Vaccines, Synthetic

Papers overview

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2018
2018
Development of an Efficacious, Semisynthetic Glycoconjugate Vaccine Candidate against Streptococcus pneumoniae Serotype 1
Infections with Streptococcus pneumoniae are a major health burden. Glycoconjugate vaccines based on capsular polysaccharides… 
Highly Cited
2017
Highly Cited
2017
A semisynthetic Streptococcus pneumoniae serotype 8 glycoconjugate vaccine
Automated glycan assembly enabled antibody reverse engineering to develop a semisynthetic carbohydrate–based vaccine against the… 
2015
2015
Effect of Natural and Semisynthetic Pseudoguianolides on the Stability of NF-κB:DNA Complex Studied by Agarose Gel Electrophoresis
The nuclear factor κB (NF-κB) is a promising target for drug discovery. NF-κB is a heterodimeric complex of RelA and p50 subunits… 
2014
2014
A new family of choline kinase inhibitors with antiproliferative and antitumor activity derived from natural products
BackgroundCholine kinase alpha (ChoKα) is a critical enzyme in the synthesis of phosphatidylcholine, a major structural component… 
2013
2013
High-fat diet action on adiposity, inflammation, and insulin sensitivity depends on the control low-fat diet.
Highly Cited
2007
Highly Cited
2007
Redirection of carotenoid metabolism for the efficient production of taxadiene [taxa-4(5),11(12)-diene] in transgenic tomato fruit
The taxanes are a group of polycyclic diterpenes produced by various species of yew. The potent anticancer drug paclitaxel… 
2006
2006
Semisynthetic sphingoglycolipid LIGA20 is neuroprotective against human immunodeficiency virus‐gp120‐mediated apoptosis
Apoptosis and neuronal atrophy are commonly seen in patients infected with the human immunodeficiency virus type 1 (HIV‐1) in the… 
Highly Cited
2000
Highly Cited
2000
Mycobacterial contamination of metalworking fluids: involvement of a possible new taxon of rapidly growing mycobacteria.
Contamination of air and metalworking fluid (MWF) systems with a rapidly growing mycobacterium (RGM) was detected in 1995 in a… 
1984
1984
Semisynthetic derivatives of glucagon. The contribution of histidine-1 to hormone conformation and activity.
Highly Cited
1979
Highly Cited
1979
Phase II study of VP-16-213 in childhood malignant disease: a Children's Cancer Study Group Report.
VP-16-213, a semisynthetic podophyliotoxin, was tested for antitumor and clinical toxicity in 126 children. The drug was… 
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