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Infections with Streptococcus pneumoniae are a major health burden. Glycoconjugate vaccines based on capsular polysaccharides… Expand Automated glycan assembly enabled antibody reverse engineering to develop a semisynthetic carbohydrate–based vaccine against the… Expand The nuclear factor κB (NF-κB) is a promising target for drug discovery. NF-κB is a heterodimeric complex of RelA and p50 subunits… Expand BackgroundCholine kinase alpha (ChoKα) is a critical enzyme in the synthesis of phosphatidylcholine, a major structural component… Expand Animal studies using a high-fat diet (HFD) have studied the effects of lipid overconsumption by comparing a defined HFD either… Expand The taxanes are a group of polycyclic diterpenes produced by various species of yew. The potent anticancer drug paclitaxel… Expand Apoptosis and neuronal atrophy are commonly seen in patients infected with the human immunodeficiency virus type 1 (HIV‐1) in the… Expand Contamination of air and metalworking fluid (MWF) systems with a rapidly growing mycobacterium (RGM) was detected in 1995 in a… Expand Semisynthetic N epsilon- acetimidoglucagon was prepared from the [des- His1 ]analogue by coupling the N-hydroxysuccinimide ester… Expand VP-16-213, a semisynthetic podophyliotoxin, was tested for antitumor and clinical toxicity in 126 children. The drug was… Expand