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Sclerostin

Sclerostin (213 aa, ~24 kDa) is encoded by the human SOST gene. This protein plays a role in the regulation of bone growth and Wnt signaling pathways… 
National Institutes of Health

Papers overview

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2018
2018
Fibroblast growth factor 2 (FGF-2) is known to be released from cartilage upon injury and is able to influence chondrocyte gene… 
2017
2017
Treatment with sclerostin antibody (romosozumab) increases bone formation while reducing bone resorption, leading to increases in… 
2016
2016
Introduction Bone diseases commonly detected in chronic renal failure patients and increases a patient’s risk for cardiovascular… 
2014
2014
Sclerostin is a product of mature osteocytes embedded in mineralised bone and is a negative regulator of bone mass and osteoblast…