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SOST gene

Known as: VBCH, SCLEROSTIN, Sclerostin Gene 
This gene plays a role in bone growth.
National Institutes of Health

Related topics

Related topics

7 relations
Environment-to-Cell CommunicationSclerosteosisSclerostinSclerostin Measurement

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SOST wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Temporal changes in systemic and local expression of bone turnover markers during six months of sclerostin antibody administration to ovariectomized rats.
Highly Cited
2014
Highly Cited
2014
Bone marrow plasma macrophage inflammatory protein protein-1 alpha(MIP-1 alpha) and sclerostin in multiple myeloma: relationship with bone disease and clinical characteristics.
2013
2013
Comparative effect of zoledronic acid versus denosumab on serum sclerostin and dickkopf-1 levels of naive postmenopausal women with low bone mass: a randomized, head-to-head clinical trial.
CONTEXT Decreased bone formation due to a coupling effect limits bone mass increases after antiresorptive treatment. OBJECTIVE… 
Review
2012
Review
2012
Regulatory pathways associated with bone loss and bone marrow adiposity caused by aging, chemotherapy, glucocorticoid therapy and radiotherapy.
The bone marrow is a complex environment that houses haematopoietic and mesenchymal cell populations and regulates bone turnover… 
Review
2011
Review
2011
Targeting sclerostin as potential treatment of osteoporosis
In recent years, study of rare bone diseases has led to the identification of signalling pathways that regulate bone formation… 
Highly Cited
2011
Highly Cited
2011
Effects of estrogen on osteoprogenitor cells and cytokines/bone-regulatory factors in postmenopausal women.
2011
2011
Relation of Age, Gender, and Bone Mass to Circulating Sclerostin Levels in Women and Men
Highly Cited
2010
Highly Cited
2010
Sclerostin is a direct target of osteoblast-specific transcription factor osterix.
2010
2010
SOST and DKK: Antagonists of LRP Family Signaling as Targets for Treating Bone Disease
The study of rare human genetic disorders has often led to some of the most significant advances in biomedical research. One such… 
Highly Cited
2009
Highly Cited
2009
A Short Treatment With an Antibody to Sclerostin Can Inhibit Bone Loss in an Ongoing Model of Colitis
Chronic inflammation leads to bone loss, and increased fracture rates have been reported in a number of human chronic… 
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