Sarkolysin

Known as: Sarcolysin, Merphalan, Sarcolysine 
The isomeric form of melphalan, with alkylating activity. Sarcolysin crosslinks DNA, thereby causing an inhibition in DNA replication and eventually… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1954-2017
05101519542016

Papers overview

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2011
2011
The International Agency for Research on Cancer has classified several antineoplastic drugs in Group 1 (human carcinogens), among… (More)
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2003
2003
Peptichemio, a mixture of six short oligopeptides all comprising the alkylating amino acid m-L-sarcolysin, has shown clinical… (More)
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2000
2000
The overexpression of lectins by malignant cells compared with normal ones can be used for the targeting of drug-loaded liposomes… (More)
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1997
1997
ID50 and ID90 values for L-prolyl-L-m-[bis(chloroethyl)amino]-phenylalanyl-L-norvaline ethyl ester HCl (MF13), were determined in… (More)
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1993
1993
Peptichemio (PTC) is a mixture of six synthetic oligopeptides, each of which contains the alkylating residuem-[di(2-chloroethyl… (More)
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1991
1991
Alteration of the melphalan molecule by shifting the di(2-choroethyl)aminogroup from the para- to the meta-position of the… (More)
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1991
1991
Peptichemio is a complex of six peptides containing m-L-sarcolysin which is used in cancer chemotherapy. One of the peptides, L… (More)
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1985
1985
A coordination complex cis-dichlorodiamminedihydroxoplatinum (IV) (oxoplatinum) was first synthesized in the USSR by Chugaev and… (More)
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