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Sarkolysin

Known as: SARCOLYSIN, Merphalan, Sarcolysine 
The isomeric form of melphalan, with alkylating activity. Sarcolysin crosslinks DNA, thereby causing an inhibition in DNA replication and eventually… 
National Institutes of Health

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Melphalan

Papers overview

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2000
2000
Influence of some DNA-alkylating drugs on thermal stability, acid and osmotic resistance of the membrane of whole human erythrocytes and their ghosts.
Human erythrocytes and their resealed ghosts were alkylated under identical conditions using three groups of alkylating antitumor… 
1998
1998
Saccharide‐assisted delivery of cytotoxic liposomes to human malignant cells
The overexpression of lectins by malignant cells was applied for in vitro targeting of liposomes equipped with a saccharide… 
1997
1997
Selective tumor apoptosis by MF13, L-prolyl-L-m-[bis(chloroethyl)amino]-phenylalanyl-L-norvaline ethyl ester, a new sarcolysin containing tripeptide.
ID50 and ID90 values for L-prolyl-L-m-[bis(chloroethyl)amino]-phenylalanyl-L-norvaline ethyl ester HCl (MF13), were determined in… 
1996
1996
[Lipid derivatives of sarcolysin, methotrexate and rubomycin].
To change the pharmacokinetic properties of the known antitumor agents sarcolysine, rubomycin, and methotrexate, their lipid… 
1992
1992
[Ligands possessing affinity to specific DNA base pair sequences. IX. Synthesis of netropsin and distamycin A analogs having sarcolysin residues or a platinum(II) atom].
In search for compounds capable of forming covalent bonds with DNA AT-pair clusters, distamycin A and netropsin analogues… 
1971
1971
Contribution to the study of the Ehrlich-ascites tumor cells. A cytological and cytochemical analysis of the effects of sarcolysine.
1971
1971
Comparative cytogenetic study of the resistance of tumor cells to sarcolysine.
1968
1968
L-sarcolysin (NSC-8806) therapy for children with metastatic neuroblastoma.
1959
1959
Tumour-inhibiting Action of 1,6-Di-(2-Bromoethylamino)-1,6-Dideoxy-D-Mannitol Dihydrobromide [DBM (R13)]
ImagesFigs. 1-2 and 5 
1955
1955
[Anti-tumor action of p-bis (chloroethyl) aminophenylalanine (sarcolysin)].
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