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Sarkolysin

Known as: SARCOLYSIN, Merphalan, Sarcolysine 
The isomeric form of melphalan, with alkylating activity. Sarcolysin crosslinks DNA, thereby causing an inhibition in DNA replication and eventually… 
National Institutes of Health

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Melphalan

Papers overview

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1992
1992
[Ligands possessing affinity to specific DNA base pair sequences. IX. Synthesis of netropsin and distamycin A analogs having sarcolysin residues or a platinum(II) atom].
In search for compounds capable of forming covalent bonds with DNA AT-pair clusters, distamycin A and netropsin analogues… 
1985
1985
[High life expectancy in multiple myeloma].
The authors describe the main clinicolaboratory finding of 9 patients with multiple myeloma (MM) who survived 10 and more years… 
1985
1985
[Characteristics of the mechanism of action of complex copper (II) compounds with alpha-amino acids].
There was no direct inhibition of DNA synthesis in ascites hepatoma 22A cells after intraperitoneal injection of single doses of… 
1980
1980
Caffeine effects on the chromosomal aberrations induced in vivo by sarcolysine and methotrexate.
Wistar adult rats bearing Guérin T8 ascite tumours were intravenously inoculated with 3 mg/kg b.w. sarcolysine and respectively 5… 
1971
1971
Comparative cytogenetic study of the resistance of tumor cells to sarcolysine.
1968
1968
L-sarcolysin (NSC-8806) therapy for children with metastatic neuroblastoma.
1962
1962
Effect of N-formyl-sarcolysine on experimental tumors.
1959
1959
Tumour-inhibiting Action of 1,6-Di-(2-Bromoethylamino)-1,6-Dideoxy-D-Mannitol Dihydrobromide [DBM (R13)]
ImagesFigs. 1-2 and 5 
1958
1958
The antitumor activity of the optic isomers of sarcolysin
SummaryInvestigations were conducted on rats with transplantation of sarcoma 45. These experiments in coordination with… 
1955
1955
[Anti-tumor action of p-bis (chloroethyl) aminophenylalanine (sarcolysin)].
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