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SYN115

 
National Institutes of Health

Papers overview

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2015
2015
Quantification of indirect pathway inhibition by the adenosine A 2a antagonist SYN115 in Parkinson disease. Adenosine A 2a… Expand
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Highly Cited
2014
Highly Cited
2014
BACKGROUND Many patients with Parkinson's disease have motor fluctuations despite treatment with available drugs. Tozadenant… Expand
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Review
2013
Review
2013
Parkinson's disease (PD) is a chronic, progressive disease of the central nervous system (CNS), characterized by a slow loss of… Expand
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2012
2012
A(2A) receptor antagonists have been proposed as therapeutic tools for dopaminergically-relevant diseases, including Parkinson's… Expand
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2012
2012
Background: Positron Emission Tomography imaging studies provide evidence of reduced dopamine function in cocaine dependent… Expand
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Review
2011
Review
2011
  • Robert A. Hauser
  • The International journal of neuroscience
  • 2011
  • Corpus ID: 207419015
ABSTRACT Our current wish list for the treatment of Parkinson's disease (PD) includes therapies that will provide robust and… Expand
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Highly Cited
2010
Highly Cited
2010
Adenosine A2a receptor antagonists reduce symptom severity in Parkinson disease (PD) and animal models. Rodent studies support… Expand
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