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STOX1 gene

Known as: FLJ25162, STORKHEAD BOX 1, STOX1 
National Institutes of Health

Papers overview

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2016
2016
Endothelial cell dysfunction and cardiac hypertrophy in the STOX1 model of preeclampsia
Preeclampsia is a disease of pregnancy involving systemic endothelial dysfunction. However, cardiovascular consequences of… 
Highly Cited
2014
Highly Cited
2014
Nitroso-redox balance and mitochondrial homeostasis are regulated by STOX1, a pre-eclampsia-associated gene.
AIMS Storkhead box 1 (STOX1) is a winged-helix transcription factor that is implicated in the genetic forms of a high-prevalence… 
Highly Cited
2013
Highly Cited
2013
Preeclampsia-Like Symptoms Induced in Mice by Fetoplacental Expression of STOX1 Are Reversed by Aspirin Treatment
Preeclampsia (PE) is a common human-specific pregnancy disorder defined by hypertension and proteinuria during gestation and… 
2010
2010
The pre-eclampsia gene STOX1 controls a conserved pathway in placenta and brain upregulated in late-onset Alzheimer's disease.
Pre-eclampsia and late-onset Alzheimer's disease (LOAD) share no clinical features. In contrast to these clinical dissimilarities… 
Review
2010
Review
2010
STOX1: Key Player in Trophoblast Dysfunction Underlying Early Onset Preeclampsia with Growth Retardation
Currently, only two preeclampsia susceptibility genes (ACVR2A, STOX1) have been identified within confirmed regions with… 
Review
2008
Review
2008
Genes and the preeclampsia syndrome
Abstract Preeclampsia is specific to pregnancy and is still a leading cause of maternal and perinatal mortality and morbidity… 
Highly Cited
2008
Highly Cited
2008
STOX1 Overexpression in Choriocarcinoma Cells Mimics Transcriptional Alterations Observed in Preeclamptic Placentas
Background Mutations in STOX1 were proposed to be causal for predisposing to preeclampsia, a hypertensive disorder originating… 
Highly Cited
2007
Highly Cited
2007
Evaluation of STOX1 as a preeclampsia candidate gene in a population-wide sample
Preeclampsia is a common, pregnancy-specific vascular disorder characterised by hypertension and proteinuria. A recent report… 
2007
2007
STOX1 is not imprinted and is not likely to be involved in preeclampsia
Previous studies showed that maternally inherited mutations in the STOX1 gene are responsible for pre-eclampsia. This is… 
Highly Cited
2005
Highly Cited
2005
Maternal segregation of the Dutch preeclampsia locus at 10q22 with a new member of the winged helix gene family
Preeclampsia is a pregnancy-associated disease with maternal symptoms but placental origin. Epigenetic inheritance is involved in… 
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