• Publications
  • Influence
Maximum likelihood from incomplete data via the EM - algorithm plus discussions on the paper
Vibratory power unit for vibrating conveyers and screens comprising an asynchronous polyphase motor, at least one pair of associated unbalanced masses disposed on the shaft of said motor, with theExpand
  • 46,050
  • 2128
  • PDF
Meta-analysis in clinical trials.
This paper examines eight published reviews each reporting results from several related trials. Each review pools the results from the relevant trials in order to evaluate the efficacy of a certainExpand
  • 28,494
  • 987
  • PDF
Random-effects models for longitudinal data.
Models for the analysis of longitudinal data must recognize the relationship between serial observations on the same unit. Multivariate models with general covariance structure are often difficult toExpand
  • 7,738
  • 357
  • PDF
Applied Longitudinal Analysis
Preface.Acknowledgments.PART I: INTRODUCTION TO LONGITUDINAL AND CLUSTERED DATA.1. Longitudinal and Clustered Data.2. Longitudinal Data: Basic Concepts.PART II: LINEAR MODELS FOR LONGITUDINALExpand
  • 3,074
  • 149
Incidence of adverse events and negligence in hospitalized patients. Results of the Harvard Medical Practice Study I.
BACKGROUND As part of an interdisciplinary study of medical injury and malpractice litigation, we estimated the incidence of adverse events, defined as injuries caused by medical management, and ofExpand
  • 4,364
  • 131
  • PDF
Incidence of Adverse Drug Events and Potential Adverse Drug Events: Implications for Prevention
Objectives. —To assess incidence and preventability of adverse drug events (ADEs) and potential ADEs. To analyze preventable events to develop prevention strategies. Design. —Prospective cohortExpand
  • 2,925
  • 123
Implementing a unified approach to family‐based tests of association
We describe a broad class of family‐based association tests that are adjusted for admixture; use either dichotomous or measured phenotypes; accommodate phenotype‐unknown subjects; use nuclearExpand
  • 887
  • 119
The family based association test method: strategies for studying general genotype–phenotype associations
With possibly incomplete nuclear families, the family based association test (FBAT) method allows one to evaluate any test statistic that can be expressed as the sum of products (covariance) betweenExpand
  • 766
  • 85
The costs of adverse drug events in hospitalized patients
Objective. —To assess the additional resource utilization associated with an adverse drug event (ADE). Design. —Nested case-control study within a prospective cohort study. Participants. —The cohortExpand
  • 1,668
  • 76
A Unified Approach to Adjusting Association Tests for Population Admixture with Arbitrary Pedigree Structure and Arbitrary Missing Marker Information
A general approach to family-based examinations of association between marker alleles and traits is proposed. The approach is based on computing p values by comparing test statistics for associationExpand
  • 628
  • 70