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STEAP1 wt Allele

Known as: PRSS24, STEAP, Six Transmembrane Epithelial Antigen of the Prostate 1 wt Allele 
Human STEAP1 wild-type allele is located in the vicinity of 7q21 and is approximately 10 kb in length. This allele, which encodes metalloreductase… 
National Institutes of Health

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Related topics

1 relation
Oxidation-Reduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
STEAP Proteins: From Structure to Applications in Cancer Therapy
The human 6-transmembrane epithelial antigen of prostate (STEAP) family comprises STEAP1, STEAP2, STEAP3, and STEAP4. All of… 
Review
2012
Review
2012
The STEAP protein family: Versatile oxidoreductases and targets for cancer immunotherapy with overlapping and distinct cellular functions
The human six‐transmembrane epithelial antigen of the prostate (STEAP) protein family contains at least five homologous members… 
2010
2010
Six-transmembrane epithelial antigen of the prostate as an immunotherapeutic target for renal cell and bladder cancer.
2009
2009
STEAP mRNA detection in serum of patients with solid tumours.
2009
2009
Six-transmembrane epithelial antigen of the prostate (STEAP1 and STEAP2)-differentially expressed by murine and human mesenchymal stem cells.
Mesenchymal stem cells (MSCs) have great potential for cell-based therapies. However, lack of cell-specific markers thwarts full… 
2009
2009
STEAP 4 regulates focal adhesion kinase activation and CpG motifs within STEAP 4 promoter region are frequently methylated in DU 145 , human androgen-independent prostate cancer cells
The possible roles of STEAP4 in cancer progression have not been reported. In this study, we report that STEAP4 expression is… 
Highly Cited
2007
Highly Cited
2007
In vivo effects of vaccination with six-transmembrane epithelial antigen of the prostate: a candidate antigen for treating prostate cancer.
Immunotherapy may provide an alternative treatment for cancer patients, especially when tumors overexpress antigens that can be… 
2007
2007
Vaccination with recombinant adenoviruses and dendritic cells expressing prostate‐specific antigens is effective in eliciting CTL and suppresses tumor growth in the experimental prostate cancer
Prostate cancer is currently the most commonly diagnosed cancer in men and the second leading cause of cancer‐related death in… 
Highly Cited
2006
Highly Cited
2006
STEAP, a prostate tumor antigen, is a target of human CD8+ T cells
STEAP is a recently identified protein shown to be particularly overexpressed in prostate cancer and also present in numerous… 
Highly Cited
1999
Highly Cited
1999
STEAP: a prostate-specific cell-surface antigen highly expressed in human prostate tumors.
In search of novel genes expressed in metastatic prostate cancer, we subtracted cDNA isolated from benign prostatic hypertrophic… 
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