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SSR504734

National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Translational control depends on phosphorylation of eIF2α by PKR-like ER kinase (PERK). To examine the role of PERK in cognitive… Expand
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2011
2011
Glycine transporter-1 (GlyT-1) in glial cells regulates extracellular levels of glycine, which acts as an obligatory co-agonist… Expand
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2010
2010
Conditioned stress-induced freezing has been used as an indicator of anxiety in rodents to evaluate the anxiolytic effects of… Expand
2009
2009
The specific glycine transporter 1 (GlyT1) inhibitor, SSR504734, is highly effective in enhancing N-methyl-D-aspartate receptor… Expand
2008
2008
RationaleInhibition of the glycine transporter 1 (GlyT1) activity increases extra-cellular glycine availability in the CNS. At… Expand
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Highly Cited
2008
Highly Cited
2008
RationaleSSR103800 and SSR504734 are novel glycine transport 1 (GlyT1) inhibitors with therapeutic potential for the treatment of… Expand
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Highly Cited
2008
Highly Cited
2008
RationaleIncreasing experimental evidence suggests that impaired N-methyl-d-aspartic acid (NMDA) receptor (NMDAr) function could… Expand
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2008
2008
In the forebrain, synaptic glycine concentrations are regulated through the glycine transporter GlyT1. Because glycine is a… Expand
Highly Cited
2005
Highly Cited
2005
Noncompetitive N-methyl-D-aspartate (NMDA) blockers induce schizophrenic-like symptoms in humans, presumably by impairing… Expand
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