SRT2104

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2010-2018
02420102018

Papers overview

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2016
2016
BACKGROUND Sirtuins are a class of proteins with important physiologic roles in metabolism and inflammation. Sirtuin (silent… (More)
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2015
2015
OBJECTIVES Sirtuin 1 influences gene expression and other cellular functions through deacetylation of histone and nonhistone… (More)
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2015
2015
UNLABELLED Activation of Sirtuin (silent mating type information regulation 2 homolog) 1, or SIRT1, is an unexplored therapeutic… (More)
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2015
2015
Activation of Sirtuin1 (Sirt1), an nicotinamide adenine dinucleotide oxidized-dependent deacetylase, by natural or synthetic… (More)
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2014
2014
Increased expression of SIRT1 extends the lifespan of lower organisms and delays the onset of age-related diseases in mammals… (More)
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2014
2014
Sirtuin 1 is a nicotinamide adenine dinucleotide-dependent protein deacetylase which regulates longevity and improves metabolism… (More)
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2014
2014
AIM SRT2104 is a selective activator of SIRT1. In animal models, SRT2104 improves glucose homeostasis and increases insulin… (More)
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2013
2013
BACKGROUND We examined the effect of the oral SIRT1 activator SRT2104 on cardiovascular function in otherwise healthy cigarette… (More)
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2013
2013
AIM SRT2104 is a novel, first-in-class, highly selective small molecule activator of the NAD + dependent deacetylase SIRT1… (More)
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2012
2012
BACKGROUND SRT2104 has been developed as a selective small molecule activator of SIRT1, a NAD(+)-dependent deacetylase involved… (More)
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