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SRC wt Allele

Known as: ASVSRC1, SRC1, ASV 
Human SRC wild-type allele is located within 20q12-q13 and is approximately 61 kb in length. This allele, which encodes proto-oncogene tyrosine… 
National Institutes of Health

Related topics

Related topics

28 relations
20q12-q13Agrin PathwayAndrogen Receptor Regulation PathwayAngiotensin II Signaling Pathway

Broader (2)

SRC genec-src Genes

Papers overview

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Highly Cited
2009
Highly Cited
2009
SUMOylation of Human Peroxisome Proliferator-activated Receptor α Inhibits Its Trans-activity through the Recruitment of the Nuclear Corepressor NCoR*
The nuclear receptor peroxisome proliferator-activated receptor α (PPARα) is a key regulator of genes implicated in lipid… 
2009
2009
Direct Interdomain Interactions Can Mediate Allosterism in the Thyroid Receptor*
The thyroid (TR) and retinoid X receptors (RXR) belong to the nuclear receptor (NR) superfamily of ligand-mediated transcription… 
2006
2006
Underexpressed coactivators PGC1alpha and SRC1 impair hepatocyte nuclear factor 4 alpha function and promote dedifferentiation in human hepatoma cells.
Hepatocyte nuclear factor 4alpha (HNF4alpha) plays critical roles during liver development and in the transcriptional regulation… 
Highly Cited
2004
Highly Cited
2004
Expression of Androgen Receptor Coregulators in Prostate Cancer
Purpose: The androgen receptor (AR)-mediated signaling pathway seems to be essentially involved in the development and… 
2004
2004
A Conserved α-Helical Motif Mediates the Binding of Diverse Nuclear Proteins to the SRC1 Interaction Domain of CBP*
CREB-binding protein (CBP) and p300 contain modular domains that mediate protein-protein interactions with a wide variety of… 
2003
2003
Agonist–antagonist induced coactivator and corepressor interplay on the human androgen receptor
Highly Cited
2002
Highly Cited
2002
Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts
Members of the mammalian p160 family, such as GRIP1, are known as glucocorticoid receptor (GR) coactivators; at certain… 
Highly Cited
2001
Highly Cited
2001
Different expression of androgen receptor coactivators in human prostate.
Highly Cited
2000
Highly Cited
2000
Functional Interaction between the p160 Coactivator Proteins and the Transcriptional Enhancer Factor Family of Transcription Factors*
SRC1, initially identified as a nuclear receptor coactivator, was found to interact with a member of the transcriptional enhancer… 
Highly Cited
1998
Highly Cited
1998
Isoforms of steroid receptor co‐activator 1 differ in their ability to potentiate transcription by the oestrogen receptor
Steroid receptor co‐activator (SRC1) is one of a number of transcriptional co‐activators that are capable of potentiating the… 
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