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SR 2555

Known as: 1H-imidazole-1-acetamide, N,N-bis(2-hydroxyethyl)-2-nitro-, SR-2555 
National Institutes of Health

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Related topics

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Broader (1)

Nitroimidazoles

Papers overview

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2004
2004
Structure-pharmacokinetic relationships for misonidazole analogues in mice
SummaryWe have compared the mouse pharmacokinetics of six analogues of the hypoxic cell sensitizer misonidazole (MISO). The… 
1986
1986
Ocular penetration, toxicity, and radiosensitization effects of two hypoxic cell radiosensitizers on retinoblastoma.
Two new radiosensitizing drugs, SR-2508 and SR-2555, were studied for their in vivo toxicity and absorption properties. For both… 
1984
1984
Sensitization of normal and malignant tissue to cyclophosphamide by nitroimidazoles with different partition coefficients.
The ability of a range of 2-nitroimidazoles with similar electron affinities but widely differing partition coefficients (P) to… 
1984
1984
Oncogenic transformation systems involving mammalian cells in vitro to determine the relative risks of different treatment modalities.
Systems developed to assay oncogenic transformation in vitro represent a rapid and powerful tool to screen and compare… 
1982
1982
In vitro hypoxic cytotoxicity of nitroimidazoles: uptake and cell cycle phase specificity.
Highly Cited
1981
Highly Cited
1981
SR-2508: a 2-nitroimidazole amide which should be superior to misonidazole as a radiosensitizer for clinical use.
Highly Cited
1980
Highly Cited
1980
The pharmacokinetics and tumor and neural tissue penetrating properties of SR-2508 and SR-2555 in the dog--hydrophilic radiosensitizers potentially less toxic than misonidazole.
The behavior of three 2-nitroimidazole drugs of similar electron affinity to misonidazole but with varying octanol: water… 
Review
1980
Review
1980
Pharmacokinetics of hypoxic cell radiosensitizers: a review.
The comparative pharmacokinetics of various nitroimidazole radiosensitizers in different species are reviewed. Radiosensitization… 
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