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SR 146131

Known as: SR-146131, SR146131 
National Institutes of Health

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2 relations

Broader (2)

IndolesThiazoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Molecular Basis of Action of a Small-Molecule Positive Allosteric Modulator Agonist at the Type 1 Cholecystokinin Holoreceptor
Allosteric modulation of receptors provides mechanistic safety while effectively achieving biologic endpoints otherwise difficult… 
2002
2002
SR146131, a cholecystokinin-A receptor agonist, antagonizes prepulse inhibition deficits produced by dizocilpine and DOI
Abstract Rationale. Converging evidence has demonstrated that cholecystokinin (CCK) inhibits mesolimbic brain dopamine (DA… 
2000
2000
Characterisation of the effects of SR146131, a novel non-peptide CCK(1) receptor agonist, on IMR-32 human neuroblastoma cells.
2000
2000
Essential role of extracellular charged residues of the human CCK(1) receptor for interactions with SR 146131, SR 27897 and CCK-8S.
2000
2000
Erratum to: "The agonist SR 146131 and the antagonist SR 27897 occupy different sites on the human CCK(1) receptor"
1999
1999
SR146131: a new potent, orally active, and selective nonpeptide cholecystokinin subtype 1 receptor agonist. I. In vitro studies.
SR146131 inhibited the binding of [125I]-Bolton Hunter (BH)-sulfated cholecystokinin octapeptide (CCK-8S) for the human… 
1999
1999
SR146131: a new potent, orally active, and selective nonpeptide cholecystokinin subtype 1 receptor agonist. II. In vivo pharmacological characterization.
SR146131 is a potent and selective agonist at cholecystokinin subtype 1 (CCK1) receptors in vitro. The present study evaluates… 
1998
1998
SR146131: A new, potent, non-peptide orally active CCKA receptor agonist
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