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SR 13668

Known as: SR-13668, SR13668 
National Institutes of Health

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1 relation

Broader (1)

Carbazoles

Papers overview

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2013
2013
Enhanced oral bioavailability of the hydrophobic chemopreventive agent (SR13668) in beagle dogs.
Potency and activity of SR13668 in cancer prevention have been proven in several in vitro and in vivo cancer models. However, the… 
2012
2012
Enhanced oral bioavailability of a cancer preventive agent (SR13668) by employing polymeric nanoparticles with high drug loading.
SR13668 [2,10-Dicarbethoxy-6-methoxy-5,7-dihydro-indolo-(2,3-b)carbazole] has been proven effective in cancer prevention, but the… 
2012
2012
Abstract 2902: Polymeric nanoparticles enhance the bioavailability of the chemopreventive compound SR13668 in beagle dogs
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL Chemopreventive compound SR13668 showed promising… 
2011
2011
Phase 0 Clinical Chemoprevention Trial of the Akt Inhibitor SR13668
SR13668, an orally active Akt pathway inhibitor, has demonstrated cancer chemopreventive potential in preclinical studies. To… 
2011
2011
Abstract 4483: SR13668, a selective 12-lipoxygenase inhibitor, suppresses tumor growth by modulating the Akt signaling pathway
SR13668, an orally active cancer therapeutic agent, exhibits potent antitumor activity against various human cancer xenografts (e… 
2011
2011
SR 13668 Phase 0 Clinical Chemoprevention Trial of the Akt Inhibitor
SR13668, an orally active Akt pathway inhibitor, has demonstrated cancer chemopreventive potential in preclinical studies. To… 
2010
2010
Abstract CN02-03: Phase 0 chemoprevention trial of SR13668, a novel AKT inhibitor, in normal volunteers
Purpose: SR13668, an orally active AKT pathway inhibitor, has demonstrated cancer chemopreventive potential in preclinical… 
2009
2009
In vitro assessment of P450 induction potential of novel chemopreventive agents SR13668, 9-cis-UAB30, and pentamethychromanol in primary cultures of human hepatocytes.
2006
2006
Signaling-transduction pathways required for ex vivo expansion of human limbal explants on intact amniotic membrane.
PURPOSE Ex vivo expansion of limbal epithelial progenitor cells on amniotic membrane (AM) without 3T3 fibroblasts is a new… 
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