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SR 12813

Known as: SR-12813 
National Institutes of Health

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Broader (1)

Diphosphonates

Papers overview

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Highly Cited
2004
Highly Cited
2004
Isolation of Mutant Cells Lacking Insig-1 through Selection with SR-12813, an Agent That Stimulates Degradation of 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase*
Insig-1 and Insig-2 are membrane proteins of the endoplasmic reticulum that regulate lipid metabolism by the following two… 
1997
1997
SR-12813 lowers plasma cholesterol in beagle dogs by decreasing cholesterol biosynthesis.
1996
1996
The Novel Cholesterol-lowering Drug SR-12813 Inhibits Cholesterol Synthesis via an Increased Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase*
SR-12813 (tetra-ethyl 2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethenyl-1,1-bisphosphonate) lowers plasma cholesterol in five species… 
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