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SPRY2 wt Allele

Known as: Sprouty Homolog 2 (Drosophila) wt Allele, hSPRY2 
Human SPRY2 wild-type allele is located in the vicinity of 13q31.1 and is approximately 5 kb in length. This allele, which encodes protein sprouty… 
National Institutes of Health

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Signal TransductionSignal Transduction Inhibition

Papers overview

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2017
2017
[Establishment of a human bladder cancer cell line stably co-expressing hSPRY2 and luciferase genes and its subcutaneous tumor xenograft model in nude mice].
Objective To establish a human bladder cancer cell line stably co-expressing human sprouty2 (hSPRY2) and luciferase (Luc) genes… 
2014
2014
[Over-expression of human SPRY2 promotes the proliferation and survival of HEK293T cells].
OBJECTIVE To construct a recombinant expression vector pDC315/hSPRY2 carrying human SPRY2 (hSPRY2) gene, and transfect the… 
2004
2004
Epigenetic inactivation of the HSPRY2 gene in human prostate cancer
Proc Amer Assoc Cancer Res, Volume 45, 2004 4179 Fibroblast growth factors (FGFs) and their receptors are key modulators of… 
2003
2003
Protein-tyrosine Phosphatase-1B (PTP1B) Mediates the Anti-migratory Actions of Sprouty*
Mammalian Sprouty proteins have been shown to inhibit the proliferation and migration of cells in response to growth factors and… 
2003
2003
Inducing Sprouty degradation
Receptor tyrosine kinases are often regulated by negative feedback loops that limit their signaling duration. But cells then need… 
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