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SPR gene
Known as:
SDR38C1
, SPR
, SEPIAPTERIN REDUCTASE
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National Institutes of Health
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Sepiapterin reductase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Sepiapterin Reductase Inhibition Leading to Selective Reduction of Inflammatory Joint Pain in Mice and Increased Urinary Sepiapterin Levels in Humans and Mice
M. Fujita
,
D. Scheffer
,
+6 authors
Nick A. Andrews
2019
Corpus ID: 219814567
To evaluate the antiinflammatory and analgesic effects of sepiapterin reductase (SPR) inhibition in a mouse model of inflammatory…
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2015
2015
Effect of sulfasalazine on human neuroblastoma: analysis of sepiapterin reductase (SPR) as a new therapeutic target
Lisette P. Yco
,
D. Geerts
,
G. Mocz
,
J. Koster
,
A. Bachmann
BMC Cancer
2015
Corpus ID: 10022480
BackgroundNeuroblastoma (NB) is an aggressive childhood malignancy in children up to 5 years of age. High-stage tumors frequently…
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2009
2009
Polymorphisms of sepiapterin reductase gene alter promoter activity and may influence risk of bipolar disorder
P. McHugh
,
P. Joyce
,
M. Kennedy
Pharmacogenetics and genomics
2009
Corpus ID: 42413432
Objectives In a previous investigation, we observed altered expression of sepiapterin reductase (SPR) in cultured neural cells…
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2008
2008
Proteomic analysis of embryonic stem cell–derived neural cells exposed to the antidepressant paroxetine
P. McHugh
,
G. Rogers
,
B. Loudon
,
Dylan M Glubb
,
P. Joyce
,
M. Kennedy
Journal of neuroscience research
2008
Corpus ID: 39190654
Antidepressant drugs can have significant effects on the mood of a patient suffering from major depression or other disorders…
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Highly Cited
2006
Highly Cited
2006
The sepiapterin reductase gene region reveals association in the PARK3 locus: analysis of familial and sporadic Parkinson’s disease in European populations
M. Sharma
,
J. Mueller
,
+13 authors
T. Gasser
Journal of Medical Genetics
2006
Corpus ID: 308726
Background: Parkinson’s disease is a genetically complex disease with mixed mode of inheritance. Recently, a haplotype across the…
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Highly Cited
2004
Highly Cited
2004
Heterozygous mutation in 5’-untranslated region of sepiapterin reductase gene (SPR) in a patient with dopa-responsive dystonia
D. Steinberger
,
N. Blau
,
+4 authors
U. Müller
Neurogenetics
2004
Corpus ID: 4833737
Abstract.The search for mutations in genes coding for components of the biopterin pathway other than GTPCH1 revealed a mutation…
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2000
2000
Characterization of recombinant Dictyostelium discoideum sepiapterin reductase expressed in E. coli.
Y. A. Kim
,
H. Chung
,
+4 authors
Y. Park
Molecules and cells
2000
Corpus ID: 33851431
A cDNA clone (SSC801) putatively encoding sepiapterin reductase (SR) was obtained from the expressed sequence tag clones of…
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1998
1998
Isolation and characterization of the Drosophila melanogaster cDNA encoding the sepiapterin reductase.
C. Seong
,
Y. A. Kim
,
+6 authors
J. Yoon
Biochimica et biophysica acta
1998
Corpus ID: 31105394
1993
1993
Detection of a novel sepiapterin reductase mRNA: assay of mRNA in various cells and tissues of various species.
J. Maier
,
K. Schott
,
T. Werner
,
A. Bacher
,
I. Ziegler
Experimental cell research
1993
Corpus ID: 20071113
Fragments of cDNA coding for rat, murine, and human sepiapterin reductase (SR) were amplified by PCR via primer positioning close…
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1984
1984
Sepiapterin reductase exhibits a NADPH-dependent dicarbonyl reductase activity.
S. Katoh
,
T. Sueoka
Biochemical and biophysical research…
1984
Corpus ID: 12439880
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