FAQ

SPINK7 gene

Known as: ECRG2, SPINK7, ESOPHAGUS CANCER-RELATED GENE 2 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2017
01219962017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Expression of bcl-2 and p53 in induction of esophageal cancer cell apoptosis by ECRG2 in combination with cisplatin.
AIM To investigate the mechanisms of induction of apoptosis of esophageal cancer cells by esophageal cancer-related gene 2 (ECRG2… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • figure 5
Is this relevant?
2010
2010
ECRG2 regulates ECM degradation and uPAR/FPRL1 pathway contributing cell invasion/migration.
ECRG2 is a novel tumor suppressor gene that shows sequence similarity to KAZAL-type serine protease inhibitor. We have previously… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2010
2010
Molecular cloning and characterization of a novel esophageal cancer related gene.
We previously identified four novel cDNA fragments related to human esophageal cancer. One of the fragments was named esophageal… (More)
Is this relevant?
2009
2009
ECRG2 regulates cell migration/invasion through urokinase-type plasmin activator receptor (uPAR)/beta1 integrin pathway.
ECRG2 is a novel gene that shows sequence similarity to KAZAL-type serine protease inhibitor. We have previously demonstrated… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2008
2008
ECRG2 disruption leads to centrosome amplification and spindle checkpoint defects contributing chromosome instability.
Cancer cells contain an abnormal number of chromosomes (aneuploidy), which is a prevalent form of genetic instability in human… (More)
Is this relevant?
2008
2008
Short tandem repeat polymorphism in exon 4 of esophageal cancer related gene 2 predicts relapse of oral squamous cell carcinoma.
Short tandem repeat (STR) polymorphisms in exon 4 of esophageal cancer related gene 2 (ECRG2) are a prognostic marker for… (More)
Is this relevant?
2007
2007
ECRG2 inhibits cancer cell migration, invasion and metastasis through the down-regulation of uPA/plasmin activity.
The esophageal cancer-related gene 2 (ECRG2) is a novel gene that shows sequence similarity to KAZAL-type serine protease… (More)
Is this relevant?
2007
2007
Short tandem repeat polymorphisms of exon 4 in Kazal-type gene ECRG2 in pancreatic carcinoma and chronic pancreatitis.
BACKGROUND Short tandem repeat (STR) polymorphisms in exon 4 of the Kazal-type esophageal cancer related gene (ECRG2) have been… (More)
Is this relevant?
2005
2005
[Inhibitory effects of esophageal cancer related gene 2 on proliferation of human esophageal cancer cell EC9706].
OBJECTIVE To investigate the inhibitory role of esophageal cancer related gene 2 (ECRG2) on proliferation of human esophageal… (More)
Is this relevant?
2003
2003
ECRG2, a novel candidate of tumor suppressor gene in the esophageal carcinoma, interacts directly with metallothionein 2A and links to apoptosis.
Esophageal cancer related gene 2 (ECRG2) is a novel candidate of the tumor suppressor gene identified from human esophagus. To… (More)
Is this relevant?