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SPI-77, liposomal

Known as: SPI 077, SPI-077, SPI077 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Cisplatincisplatin liposomal
Stealth liposomal cisplatin

Papers overview

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2011
2011
Abstract 373: Allometric scaling of the pharmacokinetics of pegylated liposomal anticancer drugs
Background: Pegylated liposomal formulations contain lipid conjugated to polyethylene glycol. These formulations of anticancer… 
2007
2007
Plasma , Tumor , andTissue Disposition of STEALTHLiposomal CKD-602 ( S-CKD 602 ) and Nonliposomal CKD-602 in Mice Bearing A 375 HumanMelanoma Xenografts
Purpose: S-CKD602 is a STEALTH liposomal formulation of CKD-602, a camptothecin analogue. The cytotoxicity of camptothecin… 
2005
2005
Effect of low-dose tumor necrosis factor-alpha in combination with STEALTH liposomal cisplatin (SPI-077) on soft-tissue- and osteosarcoma-bearing rats.
Cisplatin is a widely used agent for treatment of solid tumors, but its clinical utility is limited by toxicity. Preclinical… 
2004
2004
New liposomal formulations of cisplatin with improved therapeutic index
4612 A polyethyleneglycol modified (PEGylated) liposomal cisplatin (CDDP), SPI-77 (Alza, now Johnson & Johnson), was evaluated by… 
2000
2000
A phase I study of STEALTH cisplatin (SPI-77) and vinorelbine in patients with advanced non small-cell lung cancer.
STEALTH cisplatin (SPI-77) is a liposomal formulation of cisplatin that has activity in animal models of non small-cell lung… 
1999
1999
Antitumor activity of Herceptin in combination with STEALTH liposomal cisplatin or nonliposomal cisplatin in a HER2 positive human breast cancer model.
1999
1999
Meeting report on 8th International Symposium on Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy.
The platinum-based drugs, cisplatin and carboplatin, represent major agents in the chemotherapeutic treatment of a variety of… 
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