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SPI-1620
Known as:
Endothelin B Receptor Agonist SPI-1620
A highly selective peptide agonist of the endothelin-B receptor. Endothelin B receptor agonist SPI-1620 binds to endothelin-B receptors on…
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National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
IRL 1620
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Phase 2 study of combination SPI-1620 with docetaxel as second-line advanced biliary tract cancer treatment
Richard Kim
,
E. Chiorean
,
+5 authors
D. Portnoy
British Journal of Cancer
2017
Corpus ID: 205109900
Background:This multicentre, open-label study evaluated the efficacy and safety of SPI-1620, an analogue of endothelin-1…
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2012
2012
IRL-1620, an endothelin-B receptor agonist, enhanced radiation induced reduction in tumor volume in Dalton's Lymphoma Ascites tumor model.
A. Gulati
,
E. Sunila
,
G. Kuttan,
Arzneimittel-Forschung
2012
Corpus ID: 3253841
ETB receptor agonist, IRL-1620 (or SPI-1620) presently in US Phase 1 clinical trial, has been demonstrated to selectively and…
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2009
2009
Abstract #2333: Determination of SPI-1620 mediated blood flow increase in tumors using PET imaging
Duff Davis
,
D. Lewis
,
A. Sandler
,
L. Lenaz
,
G. Reddy
2009
Corpus ID: 73853133
AACR Annual Meeting-- Apr 18-22, 2009; Denver, CO Aim : The ETB receptor peptide agonist, SPI-1620, has been demonstrated to…
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2007
2007
Effect of SPI-1620 on tumor perfusion and uptake of paclitaxel in a melanoma model
N. Rajeshkumar
,
G. Matwyshyn
,
A. Gulati
,
G. Reddy
,
L. Lenaz
2007
Corpus ID: 90125386
B3 Background: SPI-1620 (also known as IRL-1620) is a selective ETB receptor agonist that has been reported to selectively…
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