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SPI-1620

Known as: Endothelin B Receptor Agonist SPI-1620 
A highly selective peptide agonist of the endothelin-B receptor. Endothelin B receptor agonist SPI-1620 binds to endothelin-B receptors on… Expand
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

IRL 1620

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Phase 2 study of combination SPI-1620 with docetaxel as second-line advanced biliary tract cancer treatment
Background:This multicentre, open-label study evaluated the efficacy and safety of SPI-1620, an analogue of endothelin-1… Expand
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2012
2012
IRL-1620, an endothelin-B receptor agonist, enhanced radiation induced reduction in tumor volume in Dalton's Lymphoma Ascites tumor model.
ETB receptor agonist, IRL-1620 (or SPI-1620) presently in US Phase 1 clinical trial, has been demonstrated to selectively and… Expand
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2009
2009
Abstract #2333: Determination of SPI-1620 mediated blood flow increase in tumors using PET imaging
AACR Annual Meeting-- Apr 18-22, 2009; Denver, CO Aim : The ETB receptor peptide agonist, SPI-1620, has been demonstrated to… Expand
2007
2007
Effect of SPI-1620 on tumor perfusion and uptake of paclitaxel in a melanoma model
B3 Background: SPI-1620 (also known as IRL-1620) is a selective ETB receptor agonist that has been reported to selectively… Expand
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