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SPAM1 wt Allele

Known as: HYA1, MGC26532, SPAG15 
Human SPAM1 wild-type allele is located in the vicinity of 7q31.3 and is approximately 46 kb in length. This allele, which encodes hyaluronidase PH… 
National Institutes of Health

Related topics

Related topics

7 relations
7q31.3Carbohydrate MetabolismCell AdhesionFertilization

Broader (1)

SPAM1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
PH20 is not expressed in murine CNS and oligodendrocyte precursor cells
Expression of Spam1/PH20 and its modulation of high/low molecular weight hyaluronan substrate have been proposed to play an… 
2016
2016
Proximal and distal regulation of the HYAL1 gene cluster by the estrogen receptor α in breast cancer cells
Chromosomal and genome abnormalities at the 3p21.3 locus are frequent events linked to epithelial cancers, including ovarian and… 
2014
2014
Characterization of pig sperm hyaluronidase and improvement of the digestibility of cumulus cell mass by recombinant pSPAM1 hyaluronidase in an in vitro fertilization assay.
2006
2006
Murine Spam1 mRNA: Involvement of AU‐rich elements in the 3′UTR and antisense RNA in its tight post‐transcriptional regulation in spermatids
Sperm adhesion molecule1 (SPAM1), the best characterized hyaluronidase gene, is abundantly expressed in the testis. We attempted… 
2002
2002
Characterization of PH-20 in canine spermatozoa and testis.
2001
2001
Equine sperm-oocyte interaction: the role of sperm surface hyaluronidase.
1999
1999
PH‐20 but not acrosin is involved in sperm penetration of the macaque zona pellucida
In this study, we investigated the functions of PH‐20 and acrosin during the interaction of macaque sperm with the zona pellucida… 
1998
1998
Rearrangement of the PH‐20 protein on the surface of macaque spermatozoa following exposure to anti‐PH‐20 antibodies or binding to zona pellucida
Capacitated cynomolgus macaque sperm have a surface hyaluronidase (PH‐20) that is evenly distributed over the entire head and can… 
Review
1997
Review
1997
Selection of antigens for use in a virus-vectored immunocontraceptive vaccine: PH-20 as a case study.
The European wild rabbit (Oryctolagus cuniculus) has become the major agricultural and environmental pest species in Australia… 
1994
1994
PH-20 and sperm hyaluronidase: a conceptual conundrum in mammalian fertilization.
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