SPAM1 wt Allele

Known as: HYA1, MGC26532, SPAG15 
Human SPAM1 wild-type allele is located in the vicinity of 7q31.3 and is approximately 46 kb in length. This allele, which encodes hyaluronidase PH… (More)
National Institutes of Health

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Highly Cited
2005
Highly Cited
2005
The angiotensin-converting enzyme (ACE) is a key regulator of blood pressure. It is known to cleave small peptides, such as… (More)
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2003
2003
Previously we demonstrated that the murine sperm adhesion molecule 1 (Spam1 or PH-20) is synthesized by the epididymal epithelium… (More)
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Highly Cited
2002
Highly Cited
2002
The function of glycosylphosphatidylinositol-anchored sperm hyaluronidase PH-20 in fertilization has long been believed to enable… (More)
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Highly Cited
1999
Highly Cited
1999
Hyaluronan (HA), a large glycosaminoglycan abundant in the extracellular matrix, is important in cell migration during embryonic… (More)
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Highly Cited
1997
Highly Cited
1997
Hyaluronidase was purified from human plasma using Triton X-114 phase extractions and ion-exchange chromatography. Monoclonal… (More)
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Review
1997
Review
1997
The sperm surface has an active role in the events of fertilization. The definition of the sperm surface in both its composition… (More)
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Highly Cited
1994
Highly Cited
1994
A typical mammalian egg is surrounded by an outer layer of about 3,000 cumulus cells embedded in an extracellular matrix rich in… (More)
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1988
1988
The rate of lateral diffusion of integral membrane proteins is constrained in cells, but the constraining factors for most… (More)
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1987
1987
PH-20 protein on the plasma membrane (PH-20PM) is restricted to the posterior head of acrosome-intact guinea pig sperm. During… (More)
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1985
1985
After the acrosome reaction, the PH-20 surface antigen of guinea pig sperm migrates from its original location on the posterior… (More)
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