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SPAM1 wt Allele

Known as: HYA1, MGC26532, SPAG15 
Human SPAM1 wild-type allele is located in the vicinity of 7q31.3 and is approximately 46 kb in length. This allele, which encodes hyaluronidase PH… Expand
National Institutes of Health

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Highly Cited
2005
Highly Cited
2005
The angiotensin-converting enzyme (ACE) is a key regulator of blood pressure. It is known to cleave small peptides, such as… Expand
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Highly Cited
2002
Highly Cited
2002
The function of glycosylphosphatidylinositol-anchored sperm hyaluronidase PH-20 in fertilization has long been believed to enable… Expand
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Highly Cited
1999
Highly Cited
1999
Hyaluronan (HA), a large glycosaminoglycan abundant in the extracellular matrix, is important in cell migration during embryonic… Expand
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Highly Cited
1999
Highly Cited
1999
Two new members of a family of putative hyaluronidase genes involved in glycosaminoglycan catabolism have been identified and… Expand
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Highly Cited
1997
Highly Cited
1997
Hyaluronidase was purified from human plasma using Triton X-114 phase extractions and ion-exchange chromatography. Monoclonal… Expand
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Review
1997
Review
1997
The sperm surface has an active role in the events of fertilization. The definition of the sperm surface in both its composition… Expand
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Highly Cited
1997
Highly Cited
1997
We recently cloned the major hyaluronidase of human plasma, which we termed HYAL1. All hyaluronidase activity could be purified… Expand
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Highly Cited
1994
Highly Cited
1994
A typical mammalian egg is surrounded by an outer layer of about 3,000 cumulus cells embedded in an extracellular matrix rich in… Expand
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Highly Cited
1990
Highly Cited
1990
On terminally differentiated sperm cells, surface proteins are segregated into distinct surface domains that include the anterior… Expand
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Highly Cited
1985
Highly Cited
1985
After the acrosome reaction, the PH-20 surface antigen of guinea pig sperm migrates from its original location on the posterior… Expand
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