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SPAM1 wt Allele

Known as: HYA1, MGC26532, SPAG15 
Human SPAM1 wild-type allele is located in the vicinity of 7q31.3 and is approximately 46 kb in length. This allele, which encodes hyaluronidase PH… 
National Institutes of Health

Related topics

Related topics

7 relations
7q31.3Carbohydrate MetabolismCell AdhesionFertilization

Broader (1)

SPAM1 gene

Papers overview

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2017
2017
Comment on: PH20 is not expressed in murine CNS and oligodendrocyte precursor cells
Comment on: PH20 is not expressed in murine CNS and oligodendrocyte precursor cells Larry S. Sherman* & Stephen A. Back Division… 
2016
2016
Global phase 3, randomized, double-blind, placebo-controlled study evaluating PEGylated recombinant human hyaluronidase PH20 (PEGPH20) plus nab-paclitaxel and gemcitabine in patients with previously…
2. Siegel R, et al. CA Cancer J Clin. 2016;66:7-30. 3. Provenzano PP, Hingorani SR. Br J Cancer. 2013;108(1):1-8. 4. Brekken C… 
2015
2015
Abstract B86: Pegylated recombinant human hyaluronidase PH20 (PEGPH20) enhances nab-paclitaxel plus gemcitabine efficacy in human pancreatic cancer xenografts
Hyaluronan (HA) over-accumulation in the extracellular matrix (ECM) of many solid tumors is associated with tumor progression and… 
2012
2012
Immuno-contraceptive potential of sperm specific LDHC 4 and SPAM-1 (PH-20) sub units in dog
PH-20 (Spam-1) antigen appears to be a bi-functional sperm plasma membrane protein with hyaluronidase activity and its role is… 
2012
2012
Abstract 3796: Pegylated human recombinant hyaluronidase PH20 reduces solid tumor hypoxia
Tumor hypoxia, the pathophysiological result of the structural and functional disruption of the tumor microcirculation and the… 
2011
2011
Abstract 442: Treatment of tumor xenografts in vivo with PEGylated human recombinant hyaluronidase PH20 (PEGPH20) does not increase the metastatic behavior of malignant cells
Hyaluronan (HA), a nonsulfated glycosaminoglycan, is a significant component of the extracellular matrix of many solid tumors. HA… 
2010
2010
Degree of Phosphorous Saturation in Intensively Cultivated Soils in Sri Lanka
The loss of Phosphorous (P) from intensively cultivated soil is one of the major causes of reducing water quality. The Degree of… 
2005
2005
Molecular cloning of the human and monkey sperm surface protein PH-20 ( ferlzation / contraceptive vaccine )
The guinea pig sperm surface protein PH-20 has an essential function in sperm adhesion to the zona pellucida of guinea pig eggs… 
2000
2000
Male vaccine studied; shot not yet a reality.
Research on male contraceptives is on a slow progress due to the difficulty in controlling the male reproductive system. While… 
1980
1980
Energetics of formation of lamellar porous microstructures in γ-Al2O3
AbstractThe formation of a lamellar porous microstructure in γ-Al2O3 during the dehydration of boehmite (γ-AlOOH) has been… 
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