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BackgroundWe conducted multiple microarray datasets analyses from clinical and xenograft tumor tissues to search for disease… Expand Mammalian target of rapamycin complex 1 (mTORC1) controls growth and survival in response to metabolic cues. Oxidative stress… Expand Cells arrested by damaged DNA need astrin to enable the cell cycle to resume. Uncovering the Damage Recovery Phosphoproteome DNA… Expand Kinastrin is identified as a major interacting partner for astrin in mitotic cells, and is required for astrin targeting to… Expand Accurate chromosome segregation during mitosis requires precise coordination of various processes, such as chromosome alignment… Expand Localization of the spindle and kinetochore proteins Astrin, SKAP, and LC8 is antagonized by Aurora B so that they target… Expand Faithful chromosome segregation in mitosis requires the formation of a bipolar mitotic spindle with stably attached chromosomes… Expand Astrin is a mitotic-spindle-associated protein expressed in most human cell lines and tissues. However, its functions in spindle… Expand We purified microtubules from a mammalian mitotic extract and obtained an amino acid sequence from each microtubule-associated… Expand Our previous work has shown that 26 of 38 cases (68.4%) of primary adenocarcinoma of the colon exhibited significantly elevated… Expand