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SORCS2 gene
Known as:
sortilin related VPS10 domain containing receptor 2
, SORCS RECEPTOR 2
, SORCS2
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National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Genes
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
SorCS2 Controls Functional Expression of Amino Acid Transporter EAAT3 and Protects Neurons from Oxidative Stress and Epilepsy-Induced Pathology
Anna R. Malik
,
K. Szydlowska
,
+10 authors
T. Willnow
Cell Reports
2019
Corpus ID: 73463711
2018
2018
Structural insights into SorCS2–Nerve Growth Factor complex formation
Nadia Leloup
,
L. Chataigner
,
B. Janssen
Nature Communications
2018
Corpus ID: 51869453
Signaling of SorCS receptors by proneurotrophin ligands regulates neuronal plasticity, induces apoptosis and is associated with…
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2017
2017
SorCS2-mediated NR2A trafficking regulates motor deficits in Huntington's disease.
Qian Ma
,
Jianmin Yang
,
+4 authors
B. Hempstead
JCI Insight
2017
Corpus ID: 26196449
Motor dysfunction is a prominent and disabling feature of Huntington's disease (HD), but the molecular mechanisms that dictate…
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Highly Cited
2016
Highly Cited
2016
SorCS2 is required for BDNF-dependent plasticity in the hippocampus
S. Glerup
,
U. Bølcho
,
+15 authors
A. Nykjaer
Molecular Psychiatry
2016
Corpus ID: 21763820
SorCS2 is a member of the Vps10p-domain receptor gene family receptors with critical roles in the control of neuronal viability…
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Highly Cited
2015
Highly Cited
2015
New suggestive genetic loci and biological pathways for attention function in adult attention‐deficit/hyperactivity disorder
S. Alemany
,
M. Ribasés
,
+8 authors
J. Sunyer
American Journal of Medical Genetics Part B…
2015
Corpus ID: 38488226
Attention deficit is one of the core symptoms of the attention‐deficit/hyperactivity disorder (ADHD). However, the specific…
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2014
2014
p75NTR, but Not proNGF, Is Upregulated Following Status Epilepticus in Mice
Melissa W Vondran
,
J. Lafrancois
,
+4 authors
B. Hempstead
ASN Neuro
2014
Corpus ID: 14965043
ProNGF and p75NTR are upregulated and induce cell death following status epilepticus (SE) in rats. However, less is known about…
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Highly Cited
2012
Highly Cited
2012
Discovery and Replication of Gene Influences on Brain Structure Using LASSO Regression
Omid Kohannim
,
D. Hibar
,
+12 authors
P. Thompson
Frontiers in Neuroscience
2012
Corpus ID: 21146
We implemented least absolute shrinkage and selection operator (LASSO) regression to evaluate gene effects in genome-wide…
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Review
2012
Review
2012
The role of intracellular trafficking and the VPS10d receptors in Alzheimer's disease.
C. Reitz
Future Neurology
2012
Corpus ID: 26183743
In Alzheimer's disease, the key pathological culprit is the amyloid-β protein, which is generated through β- and γ-secretase…
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Highly Cited
2006
Highly Cited
2006
Tumour necrosis factor alpha-converting enzyme mediates ectodomain shedding of Vps10p-domain receptor family members.
G. Hermey
,
S. Sjogaard
,
C. Petersen
,
A. Nykjaer
,
J. Gliemann
Biochemical Journal
2006
Corpus ID: 37208167
Several transmembrane molecules are cleaved at juxtamembrane extracellular sites leading to shedding of ectodomains. We analysed…
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Highly Cited
2001
Highly Cited
2001
Identification of SorCS2, a novel member of the VPS10 domain containing receptor family, prominently expressed in the developing mouse brain
Meriem Rezgaoui
,
G. Hermey
,
I. Riedel
,
W. Hampe
,
H. Schaller
,
I. Hermans-Borgmeyer
Mechanisms of Development
2001
Corpus ID: 18829884
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