SORCS2 gene

Known as: sortilin related VPS10 domain containing receptor 2, SORCS RECEPTOR 2, SORCS2 
 
National Institutes of Health

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Genes

Papers overview

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2018
2018
Highly segregated localization of the functionally related vps10p receptors sortilin and SorCS2 during neurodevelopment.
Nervous system development is a precisely orchestrated series of events requiring a multitude of intrinsic and extrinsic cues… (More)
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2017
2017
Disruption of SorCS2 reveals differences in the regulation of stereociliary bundle formation between hair cell types in the inner ear
Behavioural anomalies suggesting an inner ear disorder were observed in a colony of transgenic mice. Affected animals were… (More)
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2017
2017
SorCS2-mediated NR2A trafficking regulates motor deficits in Huntington's disease.
Motor dysfunction is a prominent and disabling feature of Huntington's disease (HD), but the molecular mechanisms that dictate… (More)
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2016
2016
SorCS2 is required for BDNF-dependent plasticity in the hippocampus
SorCS2 is a member of the Vps10p-domain receptor gene family receptors with critical roles in the control of neuronal viability… (More)
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2016
2016
Spatiotemporal patterns of sortilin and SorCS2 localization during organ development
Sortilin and SorCS2 are part of the Vps10p receptor family. They have both been studied in nervous tissue with several important… (More)
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2015
2015
New suggestive genetic loci and biological pathways for attention function in adult attention-deficit/hyperactivity disorder.
Attention deficit is one of the core symptoms of the attention-deficit/hyperactivity disorder (ADHD). However, the specific… (More)
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2014
2014
p75NTR, but Not proNGF, Is Upregulated Following Status Epilepticus in Mice
ProNGF and p75(NTR) are upregulated and induce cell death following status epilepticus (SE) in rats. However, less is known about… (More)
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Highly Cited
2012
Highly Cited
2012
Discovery and Replication of Gene Influences on Brain Structure Using LASSO Regression
We implemented least absolute shrinkage and selection operator (LASSO) regression to evaluate gene effects in genome-wide… (More)
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2006
2006
Tumour necrosis factor alpha-converting enzyme mediates ectodomain shedding of Vps10p-domain receptor family members.
Several transmembrane molecules are cleaved at juxtamembrane extracellular sites leading to shedding of ectodomains. We analysed… (More)
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2001
2001
Identification of SorCS2, a novel member of the VPS10 domain containing receptor family, prominently expressed in the developing mouse brain
We report the identification of a fourth member of the VPS10 domain containing receptor family, SorCS2, highly expressed in the… (More)
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