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SNK 860

Known as: SNK-860 
National Institutes of Health

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fidarestat

Papers overview

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2008
2008
Differential Effects of High Glucose and Methylglyoxal on Viability and Polyol Metabolism in Immortalized Adult Mouse Schwann Cells
Cultured Schwann cells under exposure to high glucose and methylglyoxal (MG) have been individually em- ployed for studying… 
Highly Cited
2006
Highly Cited
2006
The role of polyol pathway in high glucose-induced endothelial cell damages.
2004
2004
Effects of a Novel Aldose Reductase Inhibitor, Fidarestat (SNK-860), on Vibration Perception Threshold and Subjective Symptoms in Patients with Diabetic Polyneuropathy
ObjectiveTo evaluate the effects of fidarestat (SNK-860) on vibration perception threshold, as measured by C64 quantitative… 
2004
2004
Suppression of 3-deoxyglucosone and heparin-binding epidermal growth factor-like growth factor mRNA expression by an aldose reductase inhibitor in rat vascular smooth muscle cells.
1999
1999
Effect of aldose reductase inhibitors on glucose‐ induced changes in sorbitol and myo‐inositol metabolism in human neutrophils
Aim To investigate the influence of glucose and the efficacy of two different aldose reductase (AR) inhibitors, epalrestat and… 
1996
1996
SNK-860 : SYMPTOMATIC ANTIDIABETIC, ALDOSE REDUCTASE INHIBITOR
1995
1995
Effect of an aldose reductase inhibitor, SNK‐860, on deficits in the electroretinogram of diabetic rats
To determine the effect of an aldose reductase inhibitor, SNK‐860, on the worsening of the electroretinogram (ERG) during a… 
1995
1995
Effects of Glucose and SNK‐860, an Aldose Reductase Inhibitor, on the Polyol Pathway and Chemiluminescence Response of Human Neutrophils in vitro
An in vitro incubation study was conducted to investigate whether increased activity of the polyol pathway in human neutrophils… 
1994
1994
Synthesis and aldose reductase inhibitory activity of 2-substituted-6-fluoro-2,3-dihydrospiro [4H-1-benzopyran-4, 4'-imidazolidine]-2',5'-diones.
Optically active and racemic 2-substituted-6-fluoro-2,3-dihydrospiro[4H-1-benzopyran-4, 4'-imidazolidine]-2',5'-diones were… 
1994
1994
Effect of long-term treatment with a new aldose reductase inhibitor, (2S,4S)-6-fluoro-2′,5′-dioxospiro-[chroman-4,4′-imidazolidine]-2-carboxamide (SNK-860), on peripheral neuropathy in streptozotocin…
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