fidarestat

Known as: (2S,4S)-6-fluoro-2',5'-dioxospiro(chroman-4,4'-imidazolidine)-2-carboxamide, Spiro(4H-1-benzopyran-4,4'-imidazolidine)-2-carboxamide, 6-fluoro-2,3-dihydro-2',5'-dioxo-, (2S-cis)- 
 

Topic mentions per year

Topic mentions per year

1999-2017
024619992017

Papers overview

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2011
2011
We evaluated the effect of an aldose reductase inhibitor, fidarestat, on diabetic retinopathy (DR) and cataract in spontaneously… (More)
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2010
2010
PURPOSE Dysregulation of the polyol pathway has been implicated as a major cause of diabetic retinopathy. The aldose reductase… (More)
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2008
2008
This study was aimed at evaluating the potent and specific aldose reductase inhibitor fidarestat, on diabetes-associated cataract… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE Subjects with dietary obesity and pre-diabetes have an increased risk for developing both nerve conduction slowing and… (More)
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2006
2006
Fidarestat, an aldose reductase inhibitor (ARI), has been reported to improve clinical symptoms and nerve conduction deficits in… (More)
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2004
2004
In the present study, the authors examined whether treating streptozotocin-induced diabetic rats with the combination of alpha… (More)
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Highly Cited
2003
Highly Cited
2003
The study addressed the role for aldose reductase (AR) in 1) retinal oxidative stress and vascular endothelial growth factor… (More)
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2003
2003
It is important to suppress retinal vascular changes for prevention of the onset and progression of diabetic retinopathy. In the… (More)
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2001
2001
OBJECTIVE The purpose of this study was to evaluate the efficacy of fidarestat, a novel aldose reductase (AR) inhibitor, in a… (More)
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2000
2000
We examined the effects of long-term treatment with an aldose reductase inhibitor (ARI) fidarestat on functional, morphological… (More)
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