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SNCG gene

Known as: PERSYN, Synuclein, Gamma (Breast Cancer-Specific Protein 1) Gene, BREAST CANCER-SPECIFIC GENE 1 
This gene plays a role in central nervous development and has implicated in the in the pathogenesis of neurodegenerative diseases.
National Institutes of Health

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Related topics

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Breast CarcinomaCytoskeletal ModelingDegenerative Diseases, Central Nervous SystemGamma synuclein

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SNCG wt Allele

Papers overview

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2014
2014
Unconventional secretion of synuclein‐γ promotes tumor cell invasion
Synuclein‐γ (SNCG) is a chaperone protein and exists mainly in the cytoplasm. SNCG confers chemoresistance, and is a potential… 
Review
2014
Review
2014
Identification of γ-Synuclein as a Stage-Specific Marker in Bladder Cancer by Immunohistochemistry
Background Previous studies have shown that the expression level of γ-synuclein (SNCG) is associated with progression of many… 
2014
2014
Synuclein gamma protects HER2 and renders resistance to Hsp90 disruption
2012
2012
Neural protein gamma-synuclein interacting with androgen receptor promotes human prostate cancer progression
BackgroundGamma-synuclein (SNCG) has previously been demonstrated to be significantly correlated with metastatic malignancies… 
2008
2008
Rewiring the retinal ganglion cell gene regulatory network: Neurod1 promotes retinal ganglion cell fate in the absence of Math5
Retinal progenitor cells (RPCs) express basic helix-loop-helix (bHLH) factors in a strikingly mosaic spatiotemporal pattern… 
2008
2008
Applications of novel monoclonal antibodies specific for synuclein-gamma in evaluating its levels in sera and cancer tissues from colorectal cancer patients.
2006
2006
The role of CpG islands hypomethylation and abnormal expression of neuronal protein synuclein-gamma (SNCG) in ovarian cancer.
BACKGROUND The synucleins are a family of small cytoplasmic proteins that are expressed predominantly in neurons. Recently, their… 
Highly Cited
2005
Highly Cited
2005
Synuclein Gamma Inhibits the Mitotic Checkpoint Function and Promotes Chromosomal Instability of Breast Cancer Cells
SummaryAberrant expressions of the neuronal protein synuclein gamma (SNCG) in malignant mammary epithelial cells are strongly… 
2000
2000
Transcriptional suppression of synuclein γ (SNCG) expression in human breast cancer cells by the growth inhibitory cytokine oncostatin M
Previously, we have shown that synuclein γ (SNCG), a member of the brain protein synuclein family, is highly expressed in human… 
Highly Cited
1999
Highly Cited
1999
Stimulation of breast cancer invasion and metastasis by synuclein gamma.
We recently identified and cloned novel breast cancer-specific gene BCSG1 by direct differential cDNA sequencing. BCSG1 has a… 
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