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SNB-75

A glioblastoma cell line established from a 78 year old female with glioblastoma.
National Institutes of Health

Papers overview

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2017
2017
Synthesis and Antiproliferative Activity of Novel Heterocyclic Indole-Trimethoxyphenyl Conjugates
The synthesis and biological evaluation of a series of novel heterocyclic indole derivatives is described. The consolidation of… 
2013
2013
A Facile Synthesis of Deaza-Analogues of the Bisindole Marine Alkaloid Topsentin
A series of substituted ethyl 1-[(tert-butoxycarbonyl)amino]-2-methyl-5-(1-methyl-1H-indol-3-yl)-4-[(1-methyl-1H-indol-3-yl… 
2012
2012
Chem-bioinformatics and in vitro approaches for candidate optimization: a case study of NSC745689 as a promising antitumor agent
The benzothiazole scaffold has been reported to have antitumor activity in tumor-sensitive cell lines by proposed mechanism of… 
2010
2010
QSAR modeling, synthesis and bioassay of diverse leukemia RPMI-8226 cell line active agents.
2009
2009
Induction of cytotoxicity, apoptosis and cell cycle arrest by 1-t-butyl carbamoyl, 7-methyl-indole-3-ethyl isothiocyanate (NB7M) in nervous system cancer cells
Our group has recently developed 1-tbutyl carbamoyl, 7-methyl-indole-3-ethyl isothiocyanate (NB7M), a novel indole ethyl… 
2009
2009
Parallel Synthesis of O‐Phenoxyethyl and O‐Adamantyl N‐acyl Thiocarbamates Endowed with Antiproliferative Activity
In order to further explore the antiproliferative properties of O‐phenoxyethyl and O‐adamantyl acylthiocarbamates (ATCs), a… 
2005
2005
Synthesis and antiproliferative activity of [1,2,3,5]tetrazino[5,4-a]indoles, a new class of azolo-tetrazinones.
2002
2002
An efficient, convenient synthesis of novel medium-sized 13H-dibenzo[d,h][1,3,7]oxadiazecine-8,14-dione macrolides as anticipated antineoplastic agents.
1998
1998
Topostatin, a novel inhibitor of topoisomerases I and II produced by Thermomonospora alba strain No. 1520. I. Taxonomy, fermentation, isolation and biological activities.
A novel inhibitor of topoisomerases designated as topostatin was isolated from the culture filtrate of Thermomonospora alba… 
Highly Cited
1988
Highly Cited
1988
Plasminogen activator and inhibitor activity in human glioma cells and modulation by sodium butyrate.
The activity of the serine protease plasminogen activator (PA), which correlates with tumorigenicity and metastatic capacity, was… 
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