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SN12C

An adenocarcinoma cell line established from a 43 year old male patient with renal cell carcinoma extensively involving the perinephric fat.
National Institutes of Health

Papers overview

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2011
2011
Synthesis and biological evaluation of ABCD ring fragments of the kibdelones.
The kibdelones A-C (1-3) and their isomeric metabolites (cf. isokibdelone C 4) are hexacyclic tetrahydroxanthone natural products… 
2007
2007
Microenvironment Effects on Promoting Upregulation of Matrix Metalloproteinases in Bcl-2-Overexpressing Renal Cell Carcinoma as a Response to Doxorubicin Treatment Inducing the Production of…
Dysfunction in apoptosis has been suggested to play an important role in the development of a distant metastasis. The Bcl-2 gene… 
2006
2006
Oligomerization of p53 Precedes its Association with Dynein and Nuclear Accumulation
Previous studies have identified several proteins that associate with microtubules and the dynein motor complex including p53… 
1998
1998
The efficacy of 2',2'-difluorodeoxycytidine (gemcitabine) and vinblastine combined with interferon in nude mice xenografts of human renal cell carcinoma.
Recent in vitro experiments indicated strong activity of 2',2'-difluorodeoxycytidine (dFdC, gemcitabine) in human renal cell… 
Highly Cited
1997
Highly Cited
1997
Potent antitumor activity of a novel nucleoside analogue, BCH-4556 (beta-L-dioxolane-cytidine), in human renal cell carcinoma xenograft tumor models.
Beta-L-Dioxolane-cytidine (BCH-4556) is a novel anticancer nucleoside analogue with a stereochemically unnatural beta-L… 
1997
1997
All‐trans‐retinoic Acid‐dependent Inhibition of E‐Cadherin‐based Cell Adhesion with Concomitant Dephosphorylation of β‐Catenin in Metastatic Human Renal Carcinoma Cells
We previously described an in vitro invasion assay model, using a monolayer of vascular endothelial cells grown on collagen gel… 
1996
1996
Experimental and clinical efficacy of 2', 2'-difluorodeoxycytidine (gemcitabine) against renal cell carcinoma.
Preclinical and clinical studies have been performed to evaluate the efficacy of gemcitabine (2',2'-difluorodeoxycytidine; dFdC… 
Review
1991
Review
1991
Metastatic heterogeneity of human renal cell carcinoma.
The demonstration that cancers are biologically heterogeneous has a far-reaching implication for therapy. We reviewed recent data… 
1989
1989
In vivo selection of human renal cell carcinoma cells with high metastatic potential in nude mice
Studies were made to determine whether the orthotopic implantation of human renal cell carcinoma cells (HRCC) into nude mice will… 
1988
1988
Evidence for metastatic heterogeneity of human renal cell carcinoma.
We determined whether human renal cell carcinoma (HRCC) is heterogeneous and contains cells with different metastatic properties… 
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