SMN Complex

Known as: SMN core complex location, Survival of Motor Neuron Complex, survival motor neuron complex location 
A protein complex that contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and… (More)
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
Spinal muscular atrophy (SMA) is caused by mutations of the survival of motor neuron (SMN1) gene and deficiency of full-length… (More)
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Highly Cited
2008
Highly Cited
2008
Spliceosomal small nuclear ribonucleoproteins (snRNPs) are essential components of the nuclear pre-mRNA processing machinery. A… (More)
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Highly Cited
2007
Highly Cited
2007
Assembly of the Sm-class of U-rich small nuclear ribonucleoprotein particles (U snRNPs) is a process facilitated by the… (More)
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Review
2006
Review
2006
In eukaryotic cells, the biogenesis of spliceosomal small nuclear ribonucleoproteins (snRNPs) and likely other RNPs is mediated… (More)
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Review
2004
Review
2004
Small nuclear ribonucleoproteins (snRNPs) are crucial for pre-mRNA processing to mRNAs. Each snRNP contains a small nuclear RNA… (More)
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Highly Cited
2002
Highly Cited
2002
The Survival of Motor Neurons (SMN) protein, the product of the spinal muscular atrophy-determining gene, is part of a large… (More)
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Highly Cited
2002
Highly Cited
2002
The survival of motor neurons (SMN) protein is the product of the disease gene of spinal muscular atrophy and is found both in… (More)
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Highly Cited
2002
Highly Cited
2002
Gemin3 is a DEAD-box RNA helicase that binds to the Survival of Motor Neurons (SMN) protein and is a component of the SMN complex… (More)
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Highly Cited
2002
Highly Cited
2002
Although spliceosomal Sm proteins can assemble spontaneously onto UsnRNA in vitro, this process requires assisting factors in… (More)
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Highly Cited
1997
Highly Cited
1997
Spinal muscular atrophy (SMA) is an often fatal neuromuscular disease that has been directly linked to the protein product of the… (More)
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