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SMAD6 gene

Known as: MOTHERS AGAINST DECAPENTAPLEGIC, DROSOPHILA, HOMOLOG OF, 6, SMAD, Mothers Against DPP Homolog 6 (Drosophila) Gene, SMAD6 
This gene is involved in signal transduction and regulation of transcription. It also plays a role in development.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Bicuspid aortic valve (BAV) is the most common congenital heart defect. Although many BAV patients remain asymptomatic, at least… Expand
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Review
2016
Review
2016
To identify candidate genes for intellectual disability, we performed a meta-analysis on 2,637 de novo mutations, identified from… Expand
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Highly Cited
2016
Highly Cited
2016
Premature fusion of the cranial sutures (craniosynostosis), affecting 1 in 2000 newborns, is treated surgically in infancy to… Expand
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Highly Cited
2003
Highly Cited
2003
Smad6 and Smad7 are inhibitory Smads induced by transforming growth factor beta-Smad signal transduction pathways in a negative… Expand
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Highly Cited
2000
Highly Cited
2000
Smad6 is an inhibitory Smad that is induced by bone morphogenetic proteins (BMPs) and interferes with BMP signaling. We have… Expand
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Highly Cited
1999
Highly Cited
1999
Smad6 and Smad7 prevent ligand-induced activation of signal-transducing Smad proteins in the transforming growth factor-beta… Expand
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Highly Cited
1998
Highly Cited
1998
Smad6 and Smad7 function as intracellular antagonists in transforming growth factor-beta (TGF-beta) signaling. Here we report the… Expand
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Highly Cited
1997
Highly Cited
1997
SMAD proteins have been identified as signalling mediators of the TGF-beta superfamily, which is involved in a range of… Expand
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Highly Cited
1997
Highly Cited
1997
SMAD proteins have been identified as signalling mediators of the TGF-β superfamily, which is involved in a range of biological… Expand
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Highly Cited
1997
Highly Cited
1997
Much excitement has recently been generated by the discovery of the Smad genes, encoding proteins that transduce signals from the… Expand
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