SMAD6 protein, human

Known as: MAD, Mothers Against Decapentaplegic Homolog 6 Protein, SMA- and MAD-Related Protein 6, Mothers Against Decapentaplegic Homolog 6 Protein 
Encoded by MADH6 Gene (SMAD Family), ubiquitous (predominantly vascular endothelium) SMAD6 Protein Isoforms A (496-aa 53.5-kD) and B (235-aa) act… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2017
051019772017

Papers overview

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2006
2006
Runx2 is a bone-specific transcription factor that plays a critical role in bone development, postnatal bone formation, and… (More)
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2003
Highly Cited
2003
OBJECTIVE Osteoarthritis (OA) is a joint disease characterized by osteophyte development, fibrosis, and articular cartilage… (More)
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2002
2002
Inhibitory Smads (I-Smads), including Smad6 and Smad7, were initially characterized as cytoplasmic antagonists in the… (More)
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Highly Cited
2001
Highly Cited
2001
Inhibitory Smads (I-Smads) repress signaling by cytokines of the transforming growth factor-beta (TGF-beta) superfamily. I-Smads… (More)
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Highly Cited
2000
Highly Cited
2000
Smad proteins are intracellular mediators of signalling initiated by Tgf-βsuperfamily ligands (Tgf-βs, activins and bone… (More)
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Highly Cited
2000
Highly Cited
2000
Smad6 and Smad7, a subgroup of Smad proteins, antagonize the signals elicited by transforming growth factor-beta. These two Smads… (More)
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Highly Cited
1999
Highly Cited
1999
Smad6 and Smad7 prevent ligand-induced activation of signal-transducing Smad proteins in the transforming growth factor-beta… (More)
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Highly Cited
1998
Highly Cited
1998
Bone morphogenetic protein (BMP) receptors signal by phosphorylating Smad1, which then associates with Smad4; this complex moves… (More)
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Highly Cited
1997
Highly Cited
1997
SMAD proteins have been identified as signalling mediators of the TGF-beta superfamily, which is involved in a range of… (More)
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Highly Cited
1997
Highly Cited
1997
SMAD proteins have been identified as signalling mediators of the TGF-β superfamily, which is involved in a range of biological… (More)
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