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SM-12502

National Institutes of Health

Papers overview

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2003
2003
Polymorphic CYP2A6 and its clinical and toxicological significance
The Pharmacogenomics Journal (2003) 3, 6–7. doi:10.1038/sj.tjp.6500154 The cytochrome P450 (CYP) enzymes play a crucial role in… 
1998
1998
Possible role of platelet-activating factor in the in vivo expression of tissue factor in neutrophils.
BACKGROUND Recently, we demonstrated that neutrophils express tissue factor (TF) in a model of acute obstructive cholangitis (AOC… 
1998
1998
Continuous binding of the PAF molecule to its receptor is necessary for the long-term aggregation of platelets.
Human and rabbit platelets fully aggregated by platelet-activating factor (PAF) underwent slow disaggregation but were rapidly… 
1996
1996
Inhibition of leukotriene formation and IL-8 release by the PAF-receptor antagonist SM-12502
We analyzed the effect of the PAF receptor antagonist (+)-cis-3,5-dimethyl-2-(3-pyridyl) thiazolidin-4-one hydrochloride (SM… 
1996
1996
Effect of the PAF-receptor antagonist SM-12502 on human platelets
We analyzed the effect of the PAF receptor antagonist (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502… 
1996
1996
Effect of SM-12502 on disseminated intravascular coagulation (DIC) in tumor-bearing rats.
To investigate the role of PAF in tumor-associated disseminated intravascular coagulation (DIC), we have established the tumor… 
1995
1995
S-oxidation of (+)-cis-3,5-dimethyl-2-(3-pyridyl)-thiazolidin-4-one hydrochloride by rat hepatic flavin-containing monooxygenase 1 expressed in yeast.
1. Rat hepatic flavin-containing monooxygenase 1 (FMO1) expressed in yeast catalyzed the S-oxidation of (+)-cis-3,5-dimethyl-2-(3… 
1995
1995
SM-12502 : a platelet activating factor antagonist
1994
1994
Effects of platelet activating factor receptor antagonists on intracellular platelet activating factor function in neutrophils.
1993
1993
Platelet-activating factor and the vascular effects of zymosan in rats.
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