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SLC9A5 gene

Known as: NHE5, SLC9A5, SOLUTE CARRIER FAMILY 9, MEMBER 5 
National Institutes of Health

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2 relations
SLC9A3 genesodium-hydrogen exchanger 5

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Endosomal pH in neuronal signaling and synaptic transmission: role of Na+/H+ exchanger NHE5
Neuronal precursor cells extend multiple neurites during development, one of which extends to form an axon whereas others develop… 
2013
2013
Endosomal acidification by Na+/H+ exchanger NHE5 regulates TrkA cell-surface targeting and NGF-induced PI3K signaling
The role of endosomal pH in neurite formation, one of the principal processes of neuronal differentiation, is unknown. This study… 
Highly Cited
2011
Highly Cited
2011
Regulation of dendritic spine growth through activity-dependent recruitment of the brain-enriched Na+/H+ exchanger NHE5
pH homeostasis in neurons plays crucial roles in normal synaptic functions. It is found that the Na+/H+ exchanger NHE5 is… 
2011
2011
Functional expression of choline transporter-like protein 1 (CTL1) in human neuroblastoma cells and its link to acetylcholine synthesis
2005
2005
beta-Arrestins bind and decrease cell-surface abundance of the Na+/H+ exchanger NHE5 isoform.
The neuronal Na(+)/H(+) exchanger NHE5 isoform not only resides in the plasma membrane but also accumulates in recycling vesicles… 
Highly Cited
2002
Highly Cited
2002
Clathrin-mediated Endocytosis and Recycling of the Neuron-specific Na+/H+ Exchanger NHE5 Isoform
Mammalian Na+/H+exchangers (NHEs) are a family of integral membrane proteins that play central roles in sodium, acid-base, and… 
Review
2001
Review
2001
Na+/H+Exchangers: Linking Osmotic Dysequilibrium to Modified Cell Function
The Na+/H+ exchangers (NHEs) are among the major ion transporters involved in cell volume regulation. NHE activation leads to a… 
Highly Cited
1999
Highly Cited
1999
Molecular Cloning and Functional Expression of a Rat Na+/H+ Exchanger (NHE5) Highly Expressed in Brain*
We report here the cloning, primary structure, heterologous expression, tissue distribution, and localization of a cDNA encoding… 
Highly Cited
1996
Highly Cited
1996
Characterization of Na+/H+ exchange activity in cultured rat hippocampal astrocytes
Astrocytes actively maintain their intracellular pH (pHi) more alkaline than expected by passive distribution of H+. Acid… 
Highly Cited
1995
Highly Cited
1995
Molecular cloning and physical and genetic mapping of a novel human Na+/H+ exchanger (NHE5/SLC9A5) to chromosome 16q22.1.
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