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SLC5A5 gene

Known as: solute carrier family 5 member 5, SLC5A5, NIS 
This gene is involved in iodide transport.
National Institutes of Health

Related topics

Related topics

10 relations
AnabolismHomo sapiensIonophore activityLigand Binding

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SLC5A5 wt Allele

Papers overview

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Highly Cited
2015
Highly Cited
2015
BRAF V600E and decreased NIS and TPO expression are associated with aggressiveness of a subgroup of papillary thyroid microcarcinoma.
BACKGROUND Thyroid cancer incidence has dramatically increased worldwide over the last two decades. The rise is mostly due to an… 
2013
2013
Thyroid follicle formation and thyroglobulin expression in multipotent endodermal stem cells.
OBJECTIVE The aim of this study was to assess the impact of transcriptional induction on thyroid follicular cell (TFC… 
2009
2009
Endogenous NIS Expression in Triple-Negative Breast Cancers
BackgroundThe sodium iodide symporter (NIS) mediates iodide transport into cells and has been identified in approximately 70% of… 
Highly Cited
2007
Highly Cited
2007
Expression of the Na+/l- symporter (NIS) is markedly decreased or absent in gastric cancer and intestinal metaplastic mucosa of Barrett esophagus
BackgroundThe sodium/iodide symporter (NIS) is a plasma membrane glycoprotein that mediates iodide (I-) transport in the thyroid… 
2006
2006
PAX8-peroxisome proliferator-activated receptor gamma (PPARgamma) disrupts normal PAX8 or PPARgamma transcriptional function and stimulates follicular thyroid cell growth.
Follicular thyroid carcinomas are associated with a chromosomal translocation that fuses the thyroid-specific transcription… 
Highly Cited
2004
Highly Cited
2004
Lack of correlation for sodium iodide symporter mRNA and protein expression and analysis of sodium iodide symporter promoter methylation in benign cold thyroid nodules.
Cold thyroid nodules (CTNs) are characterized by a reduced iodide uptake in comparison to normal thyroid tissue. The sodium… 
Highly Cited
2002
Highly Cited
2002
Differentiated Thyroid Carcinoma That Express Sodium-Iodide Symporter Have a Lower Risk of Recurrence for Children and Adolescents
The sodium-iodide symporter (NIS) is expressed by papillary (PTC) and follicular (FTC) thyroid carcinoma, and is essential for… 
2002
2002
A novel peculiar mutation in the sodium/iodide symporter gene in spanish siblings with iodide transport defect.
Previously, we reported two Spanish siblings with congenital hypothyroidism due to total failure of iodide transport. These were… 
1996
1996
Adjuvant Effects on Imazethapyr, 2,4-D and Picloram Absorption by Leafy Spurge (Euphorbia esula)
Laboratory experiments were conducted to identify adjuvants that improve absorption of imazethapyr, 2,4-D amine, and picloram by… 
Highly Cited
1985
Highly Cited
1985
Induction of chromosomal damage in Chinese hamster ovary cells by soluble and particulate nickel compounds: preferential fragmentation of the heterochromatic long arm of the X-chromosome by…
Treatment of intact Chinese hamster ovary cells with crystalline NiS and NiCl2 resulted in the induction of chromosomal… 
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