SLC38A3 wt Allele

Known as: SN1, G17, SNAT3 
Human SLC38A3 wild-type allele is located in the vicinity of 3p21.31 and is approximately 16 kb in length. This allele, which encodes sodium-coupled… (More)
National Institutes of Health

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3 relations
Homo sapiensLigand BindingMolecular Transport

Papers overview

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2016
2016
Deletion of Amino Acid Transporter ASCT2 (SLC1A5) Reveals an Essential Role for Transporters SNAT1 (SLC38A1) and SNAT2 (SLC38A2) to Sustain Glutaminolysis in Cancer Cells.
Many cancer cells depend on glutamine as they use the glutaminolysis pathway to generate building blocks and energy for anabolic… (More)
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Review
2016
Review
2016
Glutamine transporters in mammalian cells and their functions in physiology and cancer.
The SLC (solute carrier)-type transporters (~400 in number) in mammalian cells consist of 52 distinct gene families, grouped… (More)
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2009
2009
Manganese disrupts astrocyte glutamine transporter expression and function.
Glutamine (Gln) plays an important role in brain energy metabolism and as a precursor for the synthesis of neurotransmitter… (More)
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2009
2009
Potassium restriction, high protein intake, and metabolic acidosis increase expression of the glutamine transporter SNAT3 (Slc38a3) in mouse kidney.
Kidneys produce ammonium to buffer and excrete acids through metabolism of glutamine. Expression of the glutamine transporter… (More)
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Highly Cited
2008
Highly Cited
2008
Genome-wide gene expression profiling reveals renal genes regulated during metabolic acidosis.
Production and excretion of acids are balanced to maintain systemic acid-base homeostasis. During metabolic acidosis (MA) excess… (More)
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2007
2007
Regulation of renal amino acid transporters during metabolic acidosis.
The kidney plays a major role in acid-base homeostasis by adapting the excretion of acid equivalents to dietary intake and… (More)
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Review
2006
Review
2006
The glutamine commute: Lost in the tube?
The "glutamate-glutamine" cycle appears to have an important, albeit not exclusive role, in the recycling of glutamate (Glu… (More)
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2005
2005
Differential regulation of amino acid transporter SNAT3 by insulin in hepatocytes.
The liver is a metabolism and transfer center of amino acids as well as the prime target organ of insulin. In this report, we… (More)
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Highly Cited
2003
Highly Cited
2003
Gastrin induces proliferation in Barrett's metaplasia through activation of the CCK2 receptor.
BACKGROUND AND AIMS Factors associated with the development and malignant progression of Barrett's esophagus are poorly… (More)
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2002
2002
Cell-specific expression of the glutamine transporter SN1 suggests differences in dependence on the glutamine cycle.
Glutamine is involved in a variety of metabolic processes, including recycling of the neurotransmitters glutamate and gamma… (More)
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