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SLC31A1 wt Allele

Known as: COPT1, Solute Carrier Family 31 Member 1 wt Allele, Copper Transport 1 Homolog (S. cerevisiae) Gene 
Human SLC31A1 wild-type allele is located in the vicinity of 9q32 and is approximately 43 kb in length. This allele, which encodes high affinity… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
BackgroundThe copper (Cu) transporter (COPT/Ctr) gene family has an important role in the maintenance of Cu homeostasis in… Expand
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Highly Cited
2010
Highly Cited
2010
The goal of this study was to determine the role of an influx copper transporter, CTR1, in the ototoxicity induced by cisplatin… Expand
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Highly Cited
2009
Highly Cited
2009
The usefulness and efficacy of cisplatin, a chemotherapeutic drug, are limited by its toxicity to normal tissues and organs… Expand
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Highly Cited
2006
Highly Cited
2006
Studies were conducted to determine distribution of the copper transporter, Ctr1, a transmembrane protein responsible for… Expand
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Highly Cited
2004
Highly Cited
2004
Copper plays a dual role in aerobic organisms, as both an essential and a potentially toxic element. To ensure copper… Expand
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Highly Cited
2002
Highly Cited
2002
Resistance to cisplatin (DDP) is often accompanied by impaired accumulation in mammalian cells. The mechanism of impaired DDP… Expand
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Highly Cited
2002
Highly Cited
2002
The trace metal copper is an essential cofactor for a number of enzymes that have critical roles in biological processes, but it… Expand
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Highly Cited
2001
Highly Cited
2001
Copper serves as an essential cofactor for a variety of proteins in all living organisms. Previously, we described a human gene… Expand
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Highly Cited
1997
Highly Cited
1997
The molecular mechanisms responsible for the cellular uptake of copper in mammalian cells are unknown. We describe isolation of a… Expand
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Highly Cited
1995
Highly Cited
1995
At the molecular level, little is known about the transport of copper across plant membranes. We have isolated an Arabidopsis… Expand
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