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SLC22A12 gene
Known as:
OAT4L
, URATE TRANSPORTER 1
, SOLUTE CARRIER FAMILY 22 (URATE TRANSPORTER), MEMBER 12
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National Institutes of Health
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Related topics
Related topics
2 relations
SLC22A15 gene
SLC22A16 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Astilbin improves potassium oxonate-induced hyperuricemia and kidney injury through regulating oxidative stress and inflammation response in mice.
Ming Wang
,
Jing Zhao
,
N. Zhang
,
Jianghua Chen
Biomedicine & pharmacotherapy = Biomedecine…
2016
Corpus ID: 6649833
Review
2012
Review
2012
Renal transport of uric acid: evolving concepts and uncertainties.
I. A. Bobulescu
,
O. Moe
Advances in chronic kidney disease
2012
Corpus ID: 3955484
In addition to its role as a metabolic waste product, uric acid has been proposed to be an important molecule with multiple…
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Highly Cited
2008
Highly Cited
2008
Mutations in glucose transporter 9 gene SLC2A9 cause renal hypouricemia.
H. Matsuo
,
T. Chiba
,
+14 authors
N. Shinomiya
American journal of human genetics
2008
Corpus ID: 23267681
Highly Cited
2008
Highly Cited
2008
Plasma Urate Level Is Directly Regulated by a Voltage-driven Urate Efflux Transporter URATv1 (SLC2A9) in Humans*
N. Anzai
,
K. Ichida
,
+8 authors
H. Sakurai
Journal of Biological Chemistry
2008
Corpus ID: 95281
Hyperuricemia is a significant factor in a variety of diseases, including gout and cardiovascular diseases. Although renal…
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Highly Cited
2008
Highly Cited
2008
Multiple organic anion transporters contribute to net renal excretion of uric acid.
S. A. Eraly
,
V. Vallon
,
+5 authors
S. Nigam
Physiological genomics
2008
Corpus ID: 7850799
Excretion of uric acid, a compound of considerable medical importance, is largely determined by the balance between renal…
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Review
2006
Review
2006
Organic Anion Transporters of the SLC22 Family: Biopharmaceutical, Physiological, and Pathological Roles
A. Rizwan
,
G. Burckhardt
Pharmaceutical Research
2006
Corpus ID: 20057918
The human organic anion transporters OAT1, OAT2, OAT3, OAT4 and URAT1 belong to a family of poly-specific transporters mainly…
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Review
2005
Review
2005
Molecular physiology of urate transport.
M. Hediger
,
Richard J. Johnson
,
H. Miyazaki
,
H. Endou
Physiology
2005
Corpus ID: 12075898
Humans excrete uric acid as the final breakdown product of unwanted purine nucleotides. Urate scavenges potential harmful…
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Review
2005
Review
2005
Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease
A. Enomoto
,
H. Endou
Clinical and Experimental Nephrology
2005
Corpus ID: 6145651
Renal proximal and distal tubules are highly polarized epithelial cells that carry out the specialized directional transport of…
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Highly Cited
2004
Highly Cited
2004
The Multivalent PDZ Domain-containing Protein PDZK1 Regulates Transport Activity of Renal Urate-Anion Exchanger URAT1 via Its C Terminus*
N. Anzai
,
H. Miyazaki
,
+9 authors
H. Endou
Journal of Biological Chemistry
2004
Corpus ID: 43302852
The urate-anion exchanger URAT1 is a member of the organic anion transporter (OAT) family that regulates blood urate level in…
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Highly Cited
2002
Highly Cited
2002
Transgenic anopheline mosquitoes impaired in transmission of a malaria parasite
R. Shao
,
Y. Kawaguchi
,
Andrew Nixon
,
Minoru Yoshida
,
Xiao-Fan Wang
,
T. Yao
2002
Corpus ID: 2961017
We thank the patients for contributing to this study; Y. Terado for discussions on immunohistochemistry, K. Tachampa and J. Y…
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