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SLC22A12 gene

Known as: OAT4L, URATE TRANSPORTER 1, SOLUTE CARRIER FAMILY 22 (URATE TRANSPORTER), MEMBER 12 
National Institutes of Health

Related topics

Related topics

2 relations
SLC22A15 geneSLC22A16 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Astilbin improves potassium oxonate-induced hyperuricemia and kidney injury through regulating oxidative stress and inflammation response in mice.
Review
2012
Review
2012
Renal transport of uric acid: evolving concepts and uncertainties.
In addition to its role as a metabolic waste product, uric acid has been proposed to be an important molecule with multiple… 
Highly Cited
2008
Highly Cited
2008
Mutations in glucose transporter 9 gene SLC2A9 cause renal hypouricemia.
Highly Cited
2008
Highly Cited
2008
Plasma Urate Level Is Directly Regulated by a Voltage-driven Urate Efflux Transporter URATv1 (SLC2A9) in Humans*
Hyperuricemia is a significant factor in a variety of diseases, including gout and cardiovascular diseases. Although renal… 
Highly Cited
2008
Highly Cited
2008
Multiple organic anion transporters contribute to net renal excretion of uric acid.
Excretion of uric acid, a compound of considerable medical importance, is largely determined by the balance between renal… 
Review
2006
Review
2006
Organic Anion Transporters of the SLC22 Family: Biopharmaceutical, Physiological, and Pathological Roles
The human organic anion transporters OAT1, OAT2, OAT3, OAT4 and URAT1 belong to a family of poly-specific transporters mainly… 
Review
2005
Review
2005
Molecular physiology of urate transport.
Humans excrete uric acid as the final breakdown product of unwanted purine nucleotides. Urate scavenges potential harmful… 
Review
2005
Review
2005
Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease
Renal proximal and distal tubules are highly polarized epithelial cells that carry out the specialized directional transport of… 
Highly Cited
2004
Highly Cited
2004
The Multivalent PDZ Domain-containing Protein PDZK1 Regulates Transport Activity of Renal Urate-Anion Exchanger URAT1 via Its C Terminus*
The urate-anion exchanger URAT1 is a member of the organic anion transporter (OAT) family that regulates blood urate level in… 
Highly Cited
2002
Highly Cited
2002
Transgenic anopheline mosquitoes impaired in transmission of a malaria parasite
We thank the patients for contributing to this study; Y. Terado for discussions on immunohistochemistry, K. Tachampa and J. Y… 
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