SLC22A12 gene

Known as: OAT4L, URATE TRANSPORTER 1, SOLUTE CARRIER FAMILY 22 (URATE TRANSPORTER), MEMBER 12 
 
National Institutes of Health

Related topics

Related topics

2 relations
SLC22A15 geneSLC22A16 gene

Papers overview

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2016
2016
Astilbin improves potassium oxonate-induced hyperuricemia and kidney injury through regulating oxidative stress and inflammation response in mice.
Astilbin is a flavonoid compound derived from the rhizome of Smilax china L. The effects and possible molecular mechanisms of… (More)
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Review
2012
Review
2012
Renal transport of uric acid: evolving concepts and uncertainties.
In addition to its role as a metabolic waste product, uric acid has been proposed to be an important molecule with multiple… (More)
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2012
2012
Urate transporter gene SLC22A12 polymorphisms associated with obesity and metabolic syndrome in Caucasians with hypertension.
BACKGROUND/AIMS Hyperuricemia is associated with obesity and the metabolic syndrome. URAT1 is a urate transporter, and we tested… (More)
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2011
2011
Interactions of urate transporter URAT1 in human kidney with uricosuric drugs.
AIM Hyperuricaemia is a significant factor in a variety of diseases, including gout and cardiovascular diseases. The kidney plays… (More)
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2010
2010
Effect of fenofibrate on uric acid metabolism and urate transporter 1.
OBJECTIVE To examine the effects of fenofibrate, an antilipotropic drug, on uric acid metabolism in healthy male subjects and on… (More)
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2007
2007
Absence of SLC22A12 gene mutations in Greek Caucasian patients with primary renal hypouricaemia.
OBJECTIVE Primary renal hypouricaemia is a hereditary clinical disorder characterized by increased renal urate clearance due to… (More)
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2006
2006
Molecular analysis of the SLC22A12 (URAT1) gene in patients with primary gout.
OBJECTIVE To analyse the SLC22A12 (URAT1) gene in primary gout patients, first-grade relatives and healthy controls and the… (More)
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Review
2005
Review
2005
Renal urate handling: clinical relevance of recent advances.
Urate is the major inert end product of purine degradation in higher primates in contrast to most other mammals because of the… (More)
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Highly Cited
2004
Highly Cited
2004
Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion.
Renal hypouricemia is an inherited and heterogeneous disorder characterized by increased urate clearance (CUA). The authors… (More)
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Highly Cited
2002
Highly Cited
2002
Transgenic anopheline mosquitoes impaired in transmission of a malaria parasite
We thank the patients for contributing to this study; Y. Terado for discussions on immunohistochemistry, K. Tachampa and J. Y… (More)
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