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SLC16A2 gene

Known as: SLC16A2, XPCT, X-LINKED PEST-CONTAINING TRANSPORTER 
National Institutes of Health

Related topics

Related topics

2 relations
SLC16A10 geneSLC16A6 gene

Papers overview

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Highly Cited
2014
Highly Cited
2014
Transporters MCT8 and OATP1C1 maintain murine brain thyroid hormone homeostasis.
Allan-Herndon-Dudley syndrome (AHDS), a severe form of psychomotor retardation with abnormal thyroid hormone (TH) parameters, is… 
Highly Cited
2011
Highly Cited
2011
Developmental and cell type‐specific expression of thyroid hormone transporters in the mouse brain and in primary brain cells
Cellular thyroid hormone uptake and efflux are mediated by transmembrane transport proteins. One of these, monocarboxylate… 
Highly Cited
2010
Highly Cited
2010
Essential Molecular Determinants for Thyroid Hormone Transport and First Structural Implications for Monocarboxylate Transporter 8*
Monocarboxylate transporter 8 (MCT8, SLC16A2) is a thyroid hormone (TH) transmembrane transport protein mutated in Allan-Herndon… 
Review
2009
Review
2009
Minireview: Pathophysiological importance of thyroid hormone transporters.
Thyroid hormone metabolism and action are largely intracellular events that require transport of iodothyronines across the plasma… 
Highly Cited
2009
Highly Cited
2009
Neuronal 3′,3,5-Triiodothyronine (T3) Uptake and Behavioral Phenotype of Mice Deficient in Mct8, the Neuronal T3 Transporter Mutated in Allan–Herndon–Dudley Syndrome
Thyroid hormone transport into cells requires plasma membrane transport proteins. Mutations in one of these, monocarboxylate… 
Highly Cited
2008
Highly Cited
2008
Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener.
Highly Cited
2006
Highly Cited
2006
Thyroid hormone transport by the human monocarboxylate transporter 8 and its rate-limiting role in intracellular metabolism.
Cellular entry of thyroid hormone is mediated by plasma membrane transporters. We have identified rat monocarboxylate transporter… 
Highly Cited
2005
Highly Cited
2005
Allan-Herndon-Dudley syndrome and the monocarboxylate transporter 8 (MCT8) gene.
Allan-Herndon-Dudley syndrome was among the first of the X-linked mental retardation syndromes to be described (in 1944) and… 
Highly Cited
2005
Highly Cited
2005
The monocarboxylate transporter 8 linked to human psychomotor retardation is highly expressed in thyroid hormone-sensitive neuron populations.
Recent genetic analysis in several patients presenting a severe form of X-linked psychomotor retardation combined with abnormal… 
Highly Cited
2004
Highly Cited
2004
A novel syndrome combining thyroid and neurological abnormalities is associated with mutations in a monocarboxylate transporter gene.
Thyroid hormones are iodothyronines that control growth and development, as well as brain function and metabolism. Although… 
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