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SLA2 gene

Known as: SLAP2, SRC-LIKE ADAPTOR 2, SLA2 
National Institutes of Health

Papers overview

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2016
2016
Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling
Fms-like tyrosine kinase (FLT3) is a frequently mutated oncogene in acute myeloid leukemia (AML). FLT3 inhibitors display… 
2013
2013
Bem3, a Cdc42 GTPase-activating protein, traffics to an intracellular compartment and recruits the secretory Rab GTPase Sec4 to endomembranes
Summary Cell polarity is essential for many cellular functions including division and cell-fate determination. Although RhoGTPase… 
Highly Cited
2007
Highly Cited
2007
DNA Sequence Characterization and Molecular Evolution of MAT1 and MAT2 Mating-Type Loci of the Self-Compatible Ascomycete Mold Neosartorya fischeri
ABSTRACT Degenerate PCR and chromosome-walking approaches were used to identify mating-type (MAT) genes and flanking regions from… 
Highly Cited
2006
Highly Cited
2006
Modulation of Prion Formation, Aggregation, and Toxicity by the Actin Cytoskeleton in Yeast
ABSTRACT Self-perpetuating protein aggregates transmit prion diseases in mammals and heritable traits in yeast. De novo prion… 
2006
2006
Identification of Novel Mutations in ACT1 and SLA2 That Suppress the Actin-Cable-Overproducing Phenotype Caused by Overexpression of a Dominant Active Form of Bni1p in Saccharomyces cerevisiae
A formin Bni1p nucleates actin to assemble actin cables, which guide the polarized transport of secretory vesicles in budding… 
2005
2005
End4/Sla2 is involved in establishment of a new growth zone in Schizosaccharomyces pombe
The rod-shaped Schizosaccharomyces pombe cell grows in a polarized fashion from opposing ends. Correct positioning of the growth… 
2003
2003
The Sla2p talin domain plays a role in endocytosis in Saccharomyces cerevisiae.
Clathrin-binding adaptors play critical roles for endocytosis in multicellular organisms, but their roles in budding yeast have… 
2001
2001
Candida albicans INT1-Induced Filamentation in Saccharomyces cerevisiae Depends on Sla2p
ABSTRACT The Candida albicans INT1 gene is important for hyphal morphogenesis, adherence, and virulence (C. Gale, C. Bendel, M… 
Highly Cited
1995
Highly Cited
1995
MOP2 (SLA2) Affects the Abundance of the Plasma Membrane H+-ATPase of Saccharomyces cerevisiae(*)
The abundance of yeast plasma membrane H+-ATPase on the cell surface is tightly regulated. Modifier of pma1 (mop) mutants were… 
Highly Cited
1993
Highly Cited
1993
Synthetic-lethal interactions identify two novel genes, SLA1 and SLA2, that control membrane cytoskeleton assembly in Saccharomyces cerevisiae
Abplp is a yeast cortical actin-binding protein that contains an SH3 domain similar to those found in signal transduction… 
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