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SK&F 104353

Known as: SK&F-104353, SKF 104353 
 
National Institutes of Health

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Highly Cited
2000
Highly Cited
2000
Eosinophilia is a feature of airway inflammation associated with asthma. Leukotriene antagonists provide therapeutic benefit in… Expand
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Highly Cited
2000
Highly Cited
2000
The lipoxygenase-derived eicosanoids leukotrienes and lipoxins are well defined regulators of hemeodynamics and leukocyte… Expand
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Highly Cited
1998
Highly Cited
1998
The role of endogenous 5-lipoxygenase products in modulating tachykinergic neurotransmission in guinea pig isolated trachea was… Expand
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Highly Cited
1997
Highly Cited
1997
Cysteinyl leukotrienes are bioactive lipid mediators known to possess potent proinflammatory actions. Included in these are… Expand
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Highly Cited
1994
Highly Cited
1994
  • J. L. Ellis, B. Undem
  • American journal of respiratory and critical care…
  • 1994
  • Corpus ID: 22373344
The intrinsic isometric tone of human isolated intralobar bronchi was evaluated in vitro. Human bronchi (inner diameter, 3 to 12… Expand
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1993
1993
The appearance of [11,12-3H]lipoxin A4 (LXA4) specific binding sites was examined with human acute promyelocytic leukemic cell… Expand
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Highly Cited
1992
Highly Cited
1992
Leukotrienes (LT) are potent spasmogenic agents in human isolated bronchial and pulmonary venous muscle preparations. Treatment… Expand
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Highly Cited
1991
Highly Cited
1991
We have determined the effect of prior inhalation of the LTD4 antagonist SK&F 104353 on the response to aspirin ingestion in six… Expand
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Highly Cited
1989
Highly Cited
1989
Lipoxin A4 (LXA4) was competitive with [3H]leukotriene D4 (LTD4) for specific binding to cultured rat glomerular mesangial cells… Expand
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Highly Cited
1987
Highly Cited
1987
In this report, we describe the in vitro and in vivo pharmacologic profile of 2(S)-hydroxy-3(R)-[(2-carboxyethyl)thio]-3-[2-(8… Expand
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