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SIRT5 gene
Known as:
SIR2L5
, SIRT5
, SIR2, S. CEREVISIAE, HOMOLOG-LIKE 5
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National Institutes of Health
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Related topics
Related topics
1 relation
SIRT3 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function
Sushabhan Sadhukhan
,
Xiaojing Liu
,
+9 authors
Hening Lin
Proceedings of the National Academy of Sciences
2016
Corpus ID: 25377667
Significance Lysine succinylation is a recently discovered protein posttranslational modification and SIRT5 is an efficient…
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Highly Cited
2016
Highly Cited
2016
SIRT5 promotes IDH2 desuccinylation and G6PD deglutarylation to enhance cellular antioxidant defense
Li-sha Zhou
,
F. Wang
,
+10 authors
D. Ye
EMBO Reports
2016
Corpus ID: 2928735
Excess in mitochondrial reactive oxygen species (ROS) is considered as a major cause of cellular oxidative stress. NADPH, the…
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Review
2016
Review
2016
The role of mitochondrial sirtuins in health and disease.
B. Osborne
,
N. Bentley
,
M. Montgomery
,
N. Turner
Free Radical Biology & Medicine
2016
Corpus ID: 207684104
Highly Cited
2015
Highly Cited
2015
SIRT5 regulation of ammonia-induced autophagy and mitophagy
L. Polletta
,
E. Vernucci
,
+16 authors
M. Tafani
Autophagy
2015
Corpus ID: 17432758
In liver the mitochondrial sirtuin, SIRT5, controls ammonia detoxification by regulating CPS1, the first enzyme of the urea cycle…
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Highly Cited
2014
Highly Cited
2014
Lysine glutarylation is a protein posttranslational modification regulated by SIRT5.
Minjia Tan
,
Chao Peng
,
+25 authors
Yingming Zhao
Cell Metabolism
2014
Corpus ID: 206842449
Highly Cited
2014
Highly Cited
2014
SIRT5 facilitates cancer cell growth and drug resistance in non-small cell lung cancer
Weidong Lu
,
Y. Zuo
,
Yufang Feng
,
Min Zhang
Tumor Biology
2014
Corpus ID: 12897443
Lung cancer is one of the leading causes of cancer-related death in developed countries. Despite decades of intensive efforts to…
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Highly Cited
2013
Highly Cited
2013
SIRT5: A Safeguard Against Oxidative Stress-Induced Apoptosis in Cardiomyocytes
Ban Liu
,
W. Che
,
+6 authors
Yawei Xu
Cellular Physiology and Biochemistry
2013
Corpus ID: 20866557
Background: SIRT5 is located in the mitochondria, and plays a crucial role in the regulation of metabolic process and cellular…
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Highly Cited
2012
Highly Cited
2012
A Molecular Mechanism for Direct Sirtuin Activation by Resveratrol
M. Gertz
,
G. Nguyen
,
+8 authors
C. Steegborn
PLoS ONE
2012
Corpus ID: 1799664
Sirtuins are protein deacetylases regulating metabolism, stress responses, and aging processes, and they were suggested to…
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Highly Cited
2011
Highly Cited
2011
Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase
Jintang Du
,
Yeyun Zhou
,
+14 authors
Hening Lin
Science
2011
Corpus ID: 206534991
Biological functions of sirtuins may involve lysine desuccinylase and demalonylase activities. Silent information regulator 2…
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Highly Cited
2008
Highly Cited
2008
Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5.
C. Schlicker
,
M. Gertz
,
P. Papatheodorou
,
Barbara Kachholz
,
C. Becker
,
C. Steegborn
Journal of Molecular Biology
2008
Corpus ID: 32694808
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